ITN1261
ITN1261
- Catalog: ITN1261
- Gene/Protein: NEK1 KIAA1901
- Product Description: Immunotag™ NEK1 Polyclonal Antibody
385.0000
Price in reward points: 385
Your shopping cart is empty!
Antibody Specification | |
Datasheet | |
Target Protein | NEK1 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from human protein . at AA range: 280-360 |
Specificity | NEK1 Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | NEK1 KIAA1901 |
Accession No. | Q96PY6 P51954 |
Description | NIMA related kinase 1(NEK1) Homo sapiens The protein encoded by this gene is a serine/threonine kinase involved in cell cycle regulation. The encoded protein is found in a centrosomal complex with FEZ1, a neuronal protein that plays a role in axonal development. Defects in this gene are a cause of polycystic kidney disease (PKD). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2010], |
Protein Expression | Bone marrow,Brain,Renal cell carcinoma,Uterus, |
Subcellular Localization | pericentriolar material,nucleus,cytoplasm,centrosome, |
Protein Function | catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,function:Phosphorylates serines and threonines, but also appears to possess tyrosine kinase activity. Implicated in the control of meiosis.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Binds to SPERT., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |