ITN1343
ITN1343
- Catalog: ITN1343
- Gene/Protein: SLC24A2 NCKX2
- Product Description: Immunotag™ NCKX2 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | NCKX2 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from human protein, at AA range: 440-520 |
Specificity | NCKX2 Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | SLC24A2 NCKX2 |
Accession No. | Q9UI40 O54701 |
Description | solute carrier family 24 member 2(SLC24A2) Homo sapiens This gene encodes a member of the calcium/cation antiporter superfamily of transport proteins. The encoded protein belongs to the SLC24 branch of exchangers, which can mediate the extrusion of one Ca2+ ion and one K+ ion in exchange for four Na+ ions. This family member is a retinal cone/brain exchanger that can mediate a light-induced decrease in free Ca2+ concentration. This protein may also play a neuroprotective role during ischemic brain injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011], |
Protein Expression | Retina, |
Subcellular Localization | plasma membrane,integral component of plasma membrane, |
Protein Function | function:Critical component of the visual transduction cascade, controlling the calcium concentration of outer segments during light and darkness. Light causes a rapid lowering of cytosolic free calcium in the outer segment of both retinal rod and cone photoreceptors and the light-induced lowering of calcium is caused by extrusion via this protein which plays a key role in the process of light adaptation. Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+).,similarity:Belongs to the sodium/potassium/calcium exchanger family. SLC24A subfamily., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |