ITN1354
ITN1354
- Catalog: ITN1354
- Gene/Protein: SLC2A8 GLUT8 GLUTX1
- Product Description: Immunotag™ GTR8 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | GTR8 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Rat,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein, at AA range: 230-310 |
| Specificity | GTR8 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | SLC2A8 GLUT8 GLUTX1 |
| Accession No. | Q9NY64 Q9JIF3 Q9JJZ1 |
| Description | solute carrier family 2 member 8(SLC2A8) Homo sapiens This gene belongs to the solute carrier 2A family, which includes intracellular glucose transporters. Based on sequence comparison, the glucose transporters are grouped into three classes and this gene is a member of class II. The encoded protein, like other members of the family, contains several conserved residues and motifs and 12 transmembrane domains with both amino and carboxyl ends being on the cytosolic side of the membrane. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Nov 2012], |
| Protein Expression | Brain,Skin,Testis, |
| Subcellular Localization | lysosomal membrane,plasma membrane,integral component of plasma membrane,synaptic vesicle,integral component of membrane,cytoplasmic vesicle membrane, |
| Protein Function | function:Insulin-regulated facilitative glucose transporter. Binds cytochalasin B in a glucose-inhibitable manner. Seems to be a dual-specific sugar transporter as it is inhibitable by fructose.,induction:In testis, down-regulated by estrogen.,similarity:Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.,subcellular location:Principally intracellular. May move between intracellular vesicles and the plasma membrane. The dileucine internalization motif is critical for intracellular sequestration.,tissue specificity:Highly expressed in testis, but not in testicular carcinoma. Lower amounts present in most other tissues., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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