ITN1357
ITN1357
ITN1357
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- Catalog: ITN1357
- Gene/Protein: SPTBN4 KIAA1642 SPTBN3
- Product Description: Immunotag™ SPTN4 Polyclonal Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein SPTN4 Clonality Polyclonal Storage/Stability -20°C/1 year Application IHC-p Recommended Dilution IHC-p 1:50-300 Concentration 1 mg/ml Reactive Species Human Host Species Rabbit Immunogen Synthesized peptide derived from part region of human protein Specificity SPTN4 Polyclonal Antibody detects endogenous levels of protein. Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. Gene Name SPTBN4 KIAA1642 SPTBN3 Accession No. Q9H254 Description spectrin beta, non-erythrocytic 4(SPTBN4) Homo sapiens Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. This gene is one member of a family of beta-spectrin genes. The encoded protein localizes to the nuclear matrix, PML nuclear bodies, and cytoplasmic vesicles. A highly similar gene in the mouse is required for localization of specific membrane proteins in polarized regions of neurons. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], Protein Expression Brain,Epithelium,Testis, Subcellular Localization cytoplasm,cytosol,plasma membrane,adherens junction,spectrin,membrane,nuclear matrix,PML body,node of Ranvier,paranode region of axon,neuronal cell body,axon initial segment,axon hillock,ext Protein Function similarity:Belongs to the spectrin family.,similarity:Contains 1 PH domain.,similarity:Contains 18 spectrin repeats.,similarity:Contains 2 CH (calponin-homology) domains.,tissue specificity:Abundantly expressed in brain and pancreatic islets., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | SPTN4 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p |
| Recommended Dilution | IHC-p 1:50-300 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | SPTN4 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | SPTBN4 KIAA1642 SPTBN3 |
| Accession No. | Q9H254 |
| Description | spectrin beta, non-erythrocytic 4(SPTBN4) Homo sapiens Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. This gene is one member of a family of beta-spectrin genes. The encoded protein localizes to the nuclear matrix, PML nuclear bodies, and cytoplasmic vesicles. A highly similar gene in the mouse is required for localization of specific membrane proteins in polarized regions of neurons. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], |
| Protein Expression | Brain,Epithelium,Testis, |
| Subcellular Localization | cytoplasm,cytosol,plasma membrane,adherens junction,spectrin,membrane,nuclear matrix,PML body,node of Ranvier,paranode region of axon,neuronal cell body,axon initial segment,axon hillock,ext |
| Protein Function | similarity:Belongs to the spectrin family.,similarity:Contains 1 PH domain.,similarity:Contains 18 spectrin repeats.,similarity:Contains 2 CH (calponin-homology) domains.,tissue specificity:Abundantly expressed in brain and pancreatic islets., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |