ITN1381
ITN1381
ITN1381
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$424.00
Price in reward points: 424
- Catalog: ITN1381
- Gene/Protein: SYN3
- Product Description: Immunotag™ SYN3 Polyclonal Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein SYN3 Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,ELISA Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000 Concentration 1 mg/ml Reactive Species Human,Rat,Mouse Host Species Rabbit Immunogen Synthesized peptide derived from part region of human protein Specificity SYN3 Polyclonal Antibody detects endogenous levels of protein. Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. Gene Name SYN3 Accession No. O14994 Q8JZP2 O70441 Description synapsin III(SYN3) Homo sapiens This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. The protein encoded by this gene shares the synapsin family domain model, with domains A, C, and E exhibiting the highest degree of conservation. The protein contains a unique domain J, located between domains C and E. Based on this gene's localization to 22q12.3, a possible schizophrenia susceptibility locus, and the established neurobiological roles of the synapsins, this family member may represent a candidate gene for schizophrenia. The TIMP3 gene is located within an intron of this gene and is transcribed in the opposite directi Protein Expression Brain, Subcellular Localization synaptic vesicle,postsynaptic density,cell junction,synaptic vesicle membrane, Protein Function function:May be involved in the regulation of neurotransmitter release and synaptogenesis.,miscellaneous:Regulated by calcium. Calcium inhibits ATP binding to the C-domain.,similarity:Belongs to the synapsin family.,subcellular location:Peripheral membrane protein localized to the cytoplasmic surface of synaptic vesicles.,subunit:Interacts with CAPON.,tissue specificity:Neuron specific. Detected predominantly in brain., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | SYN3 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Rat,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | SYN3 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | SYN3 |
| Accession No. | O14994 Q8JZP2 O70441 |
| Description | synapsin III(SYN3) Homo sapiens This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. The protein encoded by this gene shares the synapsin family domain model, with domains A, C, and E exhibiting the highest degree of conservation. The protein contains a unique domain J, located between domains C and E. Based on this gene's localization to 22q12.3, a possible schizophrenia susceptibility locus, and the established neurobiological roles of the synapsins, this family member may represent a candidate gene for schizophrenia. The TIMP3 gene is located within an intron of this gene and is transcribed in the opposite directi |
| Protein Expression | Brain, |
| Subcellular Localization | synaptic vesicle,postsynaptic density,cell junction,synaptic vesicle membrane, |
| Protein Function | function:May be involved in the regulation of neurotransmitter release and synaptogenesis.,miscellaneous:Regulated by calcium. Calcium inhibits ATP binding to the C-domain.,similarity:Belongs to the synapsin family.,subcellular location:Peripheral membrane protein localized to the cytoplasmic surface of synaptic vesicles.,subunit:Interacts with CAPON.,tissue specificity:Neuron specific. Detected predominantly in brain., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |