ITN1438
ITN1438
- Catalog: ITN1438
- Gene/Protein: PURA PUR1
- Product Description: Immunotag™ PURA Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | PURA |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human,Rat,Mouse |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from part region of human protein |
Specificity | PURA Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | PURA PUR1 |
Accession No. | Q00577 P42669 P86252 |
Description | purine rich element binding protein A(PURA) Homo sapiens This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia. [provided by RefSeq, Jul 2008], |
Protein Expression | Brain,Epithelium,Fetal liver,PCR rescued clones, |
Subcellular Localization | nuclear chromosome, telomeric region,nucleus,DNA replication factor A complex,cytoplasm,dendrite,neuronal cell body, |
Protein Function | function:This is a probable transcription activator that specifically binds the purine-rich single strand of the PUR element located upstream of the MYC gene. May play a role in the initiation of DNA replication and in recombination.,similarity:Belongs to the PUR DNA-binding protein family.,subunit:Homodimer, heterodimer with PURB and heterotrimer with PURB and YBX1/Y-box protein 1., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |