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ITN1462

ITN1462
  • Catalog: ITN1462
  • Gene/Protein: UBQLN2 N4BP4 PLIC2 HRIHFB2157
  • Product Description: Immunotag™ UBQL2 Polyclonal Antibody
385.0000
Price in reward points: 385

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Immunotag™ UBQL2 Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein UBQL2
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000
Concentration 1 mg/ml
Reactive Species Human,Mouse
Host Species Rabbit
Immunogen Synthesized peptide derived from part region of human protein
Specificity UBQL2 Polyclonal Antibody detects endogenous levels of protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Gene Name UBQLN2 N4BP4 PLIC2 HRIHFB2157
Accession No. Q9UHD9 Q9QZM0
Description ubiquilin 2(UBQLN2) Homo sapiens This gene encodes an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases; and thus, are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to bind the ATPase domain of the Hsp70-like Stch protein. [provided by RefSeq, Oct 2009],
Protein Expression Amygdala,B-cell,Fetal brain,Lung,
Subcellular Localization nucleus,cytoplasm,autophagosome,plasma membrane,cytoplasmic vesicle,
Protein Function function:Increases the half-life of proteins destined to be degraded by the proteasome; may modulate proteasome-mediated protein degradation.,induction:Highly expressed in mitotic cells from metaphase to telophase. Expression in non-mitotic cells is very low.,similarity:Contains 1 UBA domain.,similarity:Contains 1 ubiquitin-like domain.,subcellular location:Where it colocalizes with the proteasome. Associated with fibers in mitotic cells.,subunit:Binds UBE3A and BTRC. Interacts with the 19S proteasome subunit.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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