ITN1466
ITN1466
- Catalog: ITN1466
- Gene/Protein: USP14 TGT
- Product Description: Immunotag™ UBP14 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | UBP14 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from part region of human protein |
Specificity | UBP14 Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | USP14 TGT |
Accession No. | P54578 Q9JMA1 |
Description | ubiquitin specific peptidase 14(USP14) Homo sapiens This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008], |
Protein Expression | Placenta,Skin, |
Subcellular Localization | proteasome complex,cytoplasm,plasma membrane,cell surface,cytoplasmic, membrane-bounded vesicle,cytoplasmic vesicle,synapse,extracellular exosome, |
Protein Function | catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,caution:Was originally (Ref.1) thought to be a queuine tRNA-ribosyltransferase.,similarity:Belongs to the peptidase C19 family.,similarity:Contains 1 ubiquitin-like domain.,subunit:Homodimer ., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |