ITN1497
ITN1497
- Catalog: ITN1497
- Gene/Protein: UBE2R2 CDC34B UBC3B
- Product Description: Immunotag™ UB2R2 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | UB2R2 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from part region of human protein |
Specificity | UB2R2 Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | UBE2R2 CDC34B UBC3B |
Accession No. | Q712K3 Q6ZWZ2 |
Description | ubiquitin conjugating enzyme E2 R2(UBE2R2) Homo sapiens Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation. [provided by RefSeq, Jul 2008], |
Cell Pathway/ Category | Ubiquitin mediated proteolysis, |
Protein Expression | Carcinoma,Ovary,Testis, |
Subcellular Localization | cytoplasm, |
Protein Function | catalytic activity:ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.,function:Catalyzes the covalent attachment of ubiquitin to other proteins. May be involved in degradation of katenin.,pathway:Protein modification; protein ubiquitination.,similarity:Belongs to the ubiquitin-conjugating enzyme family.,subunit:When phosphorylated, interacts with beta-TrCP (BTRC)., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |