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ITN1521

  • Gene/Protein: BNIP1 NIP1 SEC20L TRG8
  • Product Description: Immunotag™ SEC20 Polyclonal Antibody
  • 280.0000
    Price in reward points: 294

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ITN1521

Immunotag™ SEC20 Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein SEC20
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000
Concentration 1 mg/ml
Reactive Species Human,Rat,Mouse
Host Species Rabbit
Immunogen Synthesized peptide derived from part region of human protein
Specificity SEC20 Polyclonal Antibody detects endogenous levels of protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Gene Name BNIP1 NIP1 SEC20L TRG8
Accession No. Q12981 Q6QD59 Q8VHI8
Description BCL2 interacting protein 1(BNIP1) Homo sapiens This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects cells from virally-induced cell death. The encoded protein also interacts with E1B 19 kDa-like sequences of BCL2, another apoptotic protector. In addition, this protein is involved in vesicle transport into the endoplasmic reticulum. Alternative splicing of this gene results in four protein products with identical N- and C-termini. [provided by RefSeq, Mar 2011],
Cell Pathway/ Category SNARE interactions in vesicular transport,
Protein Expression Kidney,
Subcellular Localization nuclear envelope,cytoplasm,mitochondrion,endoplasmic reticulum,endoplasmic reticulum membrane,integral component of endoplasmic reticulum membrane,SNARE complex,intracellular membrane-bounded organelle,
Protein Function Additional isoforms seem to exist,function:SNARE that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER. Required for maintenance of ER network. Implicated in the suppression of cell death.,miscellaneous:Silencing of BNIP1 disrupts ER morphology.,similarity:Belongs to the SEC20 family.,subunit:Component of a SNARE complex consisting of STX18, USE1L, BNIP1/SEC20L and SEC22B. Interacts directly with STX18, RINT1/TIP20L and NAPA. Interacts with ZW10 through RINT1. Interacts with BCL2 and adenovirus E1B 19 kDa protein.,tissue specificity:High levels of isoform 1 in heart, brain, liver skeletal muscle and pancreas. Moderate levels of isoform 3 in placenta, lung and kidney. High levels of isoform 4 in testis and small intestine.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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