ITN1717
ITN1717
ITN1717
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$424.00
Price in reward points: 424
- Catalog: ITN1717
- Gene/Protein: ONECUT1 HNF6 HNF6A
- Product Description: Immunotag™ HNF6 Polyclonal Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein HNF6 Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,ELISA Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000 Concentration 1 mg/ml Reactive Species Human,Mouse,Rat Host Species Rabbit Immunogen Synthesized peptide derived from human protein, at AA range: 330-410 Specificity HNF6 Polyclonal Antibody detects endogenous levels of protein. Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. Gene Name ONECUT1 HNF6 HNF6A Accession No. Q9UBC0 O08755 P70512 Description one cut homeobox 1(ONECUT1) Homo sapiens This gene encodes a member of the Cut homeobox family of transcription factors. Expression of the encoded protein is enriched in the liver, where it stimulates transcription of liver-expressed genes, and antagonizes glucocorticoid-stimulated gene transcription. This gene may influence a variety of cellular processes including glucose metabolism, cell cycle regulation, and it may also be associated with cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012], Cell Pathway/ Category Maturity onset diabetes of the young, Subcellular Localization nucleus, Protein Function function:Transcriptional activator. Binds the consensus sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR. Important for liver genes transcription.,online information:Hepatocyte nuclear factors entry,similarity:Belongs to the CUT homeobox family.,similarity:Contains 1 CUT DNA-binding domain.,similarity:Contains 1 homeobox DNA-binding domain.,subunit:Binds DNA as a monomer.,tissue specificity:Highly expressed in liver; lower expression in testis and skin., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | HNF6 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein, at AA range: 330-410 |
| Specificity | HNF6 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | ONECUT1 HNF6 HNF6A |
| Accession No. | Q9UBC0 O08755 P70512 |
| Description | one cut homeobox 1(ONECUT1) Homo sapiens This gene encodes a member of the Cut homeobox family of transcription factors. Expression of the encoded protein is enriched in the liver, where it stimulates transcription of liver-expressed genes, and antagonizes glucocorticoid-stimulated gene transcription. This gene may influence a variety of cellular processes including glucose metabolism, cell cycle regulation, and it may also be associated with cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012], |
| Cell Pathway/ Category | Maturity onset diabetes of the young, |
| Subcellular Localization | nucleus, |
| Protein Function | function:Transcriptional activator. Binds the consensus sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR. Important for liver genes transcription.,online information:Hepatocyte nuclear factors entry,similarity:Belongs to the CUT homeobox family.,similarity:Contains 1 CUT DNA-binding domain.,similarity:Contains 1 homeobox DNA-binding domain.,subunit:Binds DNA as a monomer.,tissue specificity:Highly expressed in liver; lower expression in testis and skin., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |