ITN1731
ITN1731
ITN1731
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$424.00
Price in reward points: 424
- Catalog: ITN1731
- Gene/Protein: COX7A2L COX7AR COX7RP
- Product Description: Immunotag™ COX7R Polyclonal Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein COX7R Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,ELISA Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000 Concentration 1 mg/ml Reactive Species Human,Mouse Host Species Rabbit Immunogen Synthesized peptide derived from human protein . at AA range: 10-90 Specificity COX7R Polyclonal Antibody detects endogenous levels of protein. Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. Gene Name COX7A2L COX7AR COX7RP Accession No. O14548 Q61387 Description cytochrome c oxidase subunit 7A2 like(COX7A2L) Homo sapiens Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target Cell Pathway/ Category Oxidative phosphorylation,Cardiac muscle contraction,Alzheimer's disease,Parkinson's disease,Huntington's disease, Protein Expression Lung,Placenta,Prostate,Spleen, Subcellular Localization mitochondrial inner membrane,mitochondrial respiratory chain,integral component of membrane, Protein Function function:May be a regulatory subunit of cytochrome c oxidase that mediates the higher level of energy production in target cells by estrogen.,induction:By estrogen.,similarity:Belongs to the cytochrome c oxidase VIIa family., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | COX7R |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 10-90 |
| Specificity | COX7R Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | COX7A2L COX7AR COX7RP |
| Accession No. | O14548 Q61387 |
| Description | cytochrome c oxidase subunit 7A2 like(COX7A2L) Homo sapiens Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target |
| Cell Pathway/ Category | Oxidative phosphorylation,Cardiac muscle contraction,Alzheimer's disease,Parkinson's disease,Huntington's disease, |
| Protein Expression | Lung,Placenta,Prostate,Spleen, |
| Subcellular Localization | mitochondrial inner membrane,mitochondrial respiratory chain,integral component of membrane, |
| Protein Function | function:May be a regulatory subunit of cytochrome c oxidase that mediates the higher level of energy production in target cells by estrogen.,induction:By estrogen.,similarity:Belongs to the cytochrome c oxidase VIIa family., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |