ITN1976
ITN1976
- Catalog: ITN1976
- Gene/Protein: AVP ARVP VP
- Product Description: Immunotag™ NEU2 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | NEU2 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Rat,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | NEU2 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | AVP ARVP VP |
| Accession No. | P01185 P35455 P01186 |
| Description | arginine vasopressin(AVP) Homo sapiens This gene encodes a member of the vasopressin/oxytocin family and preproprotein that is proteolytically processed to generate multiple protein products. These products include the neuropeptide hormone arginine vasopressin, and two other peptides, neurophysin 2 and copeptin. Arginine vasopressin is a posterior pituitary hormone that is synthesized in the supraoptic nucleus and paraventricular nucleus of the hypothalamus. Along with its carrier protein, neurophysin 2, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis where it is either stored or secreted into the bloodstream. The precursor is thought to be activated while it is being transported along the axon to the posterior pituitary. Arginine vasopressin acts as a growth factor by enhancing pH regulation through acid-base transport systems. It has a direct antidiuretic action on the ki |
| Protein Expression | Lung carcinoma, |
| Subcellular Localization | extracellular region,extracellular space,cytosol,secretory granule,dendrite, |
| Protein Function | disease:Defects in AVP are the cause of autosomal dominant neurohypophyseal diabetes insipidus (ADNDI) [MIM:125700]. ADNDI is characterized by persistent thirst, polydipsia and polyuria. The disease is transmitted in an autosomal dominant mode and appears to be largely if not completely penetrant.,disease:Defects in AVP are the cause of autosomal recessive neurohypophyseal diabetes insipidus (ARNDI) [MIM:125700]. ARNDI is characterized by persistent thirst, polydipsia and polyuria. Most mutations are hypothesized to trigger neurodegeneration via disruption of preproAVP-NPII processing.,function:Neurophysin 2 specifically binds vasopressin.,function:Vasopressin has a direct antidiuretic action on the kidney, it also causes vasoconstriction of the peripheral vessels.,online information:Vasopressin entry,similarity:Belongs to the vasopressin/oxytocin family., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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