Datasheet |
|
Target Protein |
PROM2 |
Clonality |
Polyclonal |
Storage/Stability |
-20°C/1 year |
Application |
WB,ELISA |
Recommended Dilution |
WB 1:500-2000 ELISA 1:5000-20000 |
Concentration |
1 mg/ml |
Reactive Species |
Human,Rat,Mouse |
Host Species |
Rabbit |
Immunogen |
Synthesized peptide derived from part region of human protein |
Specificity |
PROM2 Polyclonal Antibody detects endogenous levels of protein. |
Purification |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form |
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name |
PROM2 PROML2 UNQ2521/PRO6014 |
Accession No. |
Q8N271 Q3UUY6 Q8CJ52 |
Description |
prominin 2(PROM2) Homo sapiens This gene encodes a member of the prominin family of pentaspan membrane glycoproteins. The encoded protein localizes to basal epithelial cells and may be involved in the organization of plasma membrane microdomains. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009], |
Protein Expression |
Brain,Kidney,Prostate,Tongue, |
Subcellular Localization |
integral component of plasma membrane,microvillus,cilium,cell surface,integral component of membrane,basolateral plasma membrane,apical plasma membrane,cytoplasmic vesicle,microvillus membrane,cell projection,microspike,membrane raft,GO |
Protein Function |
PTM:Glycosylated.,similarity:Belongs to the prominin family.,subcellular location:Colocalizes with PROM1. Associates with membrane in a cholesterol-dependent manner. Localizes to the apical and basolateral membranes of epithelial cells.,subunit:Binds cholesterol.,tissue specificity:Present in saliva within small membrane particles (at protein level). Expressed in kidney, prostate, trachea, esophagus, salivary gland, thyroid gland, mammary gland adrenal gland, placenta, stomach, spinal cord and liver. In submucosal tumor, expressed in spindle-shaped or stellate stromal cells. Expressed in prostate cancer cell lines., |
Usage |
For Research Use Only! Not for diagnostic or therapeutic procedures. |