ITN2013
ITN2013
- Catalog: ITN2013
- Gene/Protein: KIRREL2 NEPH3 UNQ5827/PRO19646
- Product Description: Immunotag™ KIRR2 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | KIRR2 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | KIRR2 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | KIRREL2 NEPH3 UNQ5827/PRO19646 |
| Accession No. | Q6UWL6 Q7TSU7 |
| Description | kin of IRRE like 2 (Drosophila)(KIRREL2) Homo sapiens This gene encodes a type I transmembrane protein and member of the immunoglobulin superfamily of cell adhesion molecules. The encoded protein localizes to adherens junctions in pancreatic beta cells and regulates insulin secretion. Autoantibodies against the encoded protein have been detected in serum from patients with type 1 diabetes. This gene may also play a role in glomerular development and decreased expression of this gene has been observed in human glomerular diseases. This gene and the related opposite-strand gene nephrin (GeneID: 527362) are regulated by a bidirectional promoter. [provided by RefSeq, Jul 2016], |
| Protein Expression | Brain,Eye, |
| Subcellular Localization | plasma membrane,integral component of membrane,slit diaphragm, |
| Protein Function | similarity:Belongs to the immunoglobulin superfamily.,similarity:Contains 5 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Interacts with C-terminus of NPHS2/podocin.,tissue specificity:Highly expressed in beta-cells of the pancreatic islets., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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