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ITN2021

  • Gene/Protein: EXTL3 EXTL1L EXTR1 KIAA0519
  • Product Description: Immunotag™ EXTL3 Polyclonal Antibody
  • 280.0000
    Price in reward points: 294

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ITN2021

Immunotag™ EXTL3 Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein EXTL3
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000
Concentration 1 mg/ml
Reactive Species Human,Mouse
Host Species Rabbit
Immunogen Synthesized peptide derived from part region of human protein
Specificity EXTL3 Polyclonal Antibody detects endogenous levels of protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Gene Name EXTL3 EXTL1L EXTR1 KIAA0519
Accession No. O43909 Q9WVL6
Description exostosin like glycosyltransferase 3(EXTL3) Homo sapiens This gene encodes a single-pass membrane protein which functions as a glycosyltransferase. The encoded protein catalyzes the transfer of N-acetylglucosamine to glycosaminoglycan chains. This reaction is important in heparin and heparan sulfate synthesis. Alternative splicing results in the multiple transcript variants. [provided by RefSeq, Nov 2012],
Cell Pathway/ Category Heparan sulfate biosynthesis,
Protein Expression Amygdala,Brain,Fetus,Testis,
Subcellular Localization endoplasmic reticulum,endoplasmic reticulum membrane,integral component of membrane,
Protein Function catalytic activity:UDP-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan = UDP + alpha-N-acetyl-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan.,caution:It is uncertain whether Met-1, Met-6 or Met-20 is the initiator.,disease:Candidate gene for the breast cancer locus on chromosome 8p12-p22.,function:Probable glycosyltransferase.,online information:Exostosin-like 3,online information:GlycoGene database,pathway:Glycan metabolism; heparan sulfate biosynthesis.,similarity:Belongs to the glycosyltransferase 47 family.,tissue specificity:Ubiquitous.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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