ITN2021
ITN2021
ITN2021
from
$424.00
Price in reward points: 424
- Catalog: ITN2021
- Gene/Protein: EXTL3 EXTL1L EXTR1 KIAA0519
- Product Description: Immunotag™ EXTL3 Polyclonal Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein EXTL3 Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,ELISA Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000 Concentration 1 mg/ml Reactive Species Human,Mouse Host Species Rabbit Immunogen Synthesized peptide derived from part region of human protein Specificity EXTL3 Polyclonal Antibody detects endogenous levels of protein. Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. Gene Name EXTL3 EXTL1L EXTR1 KIAA0519 Accession No. O43909 Q9WVL6 Description exostosin like glycosyltransferase 3(EXTL3) Homo sapiens This gene encodes a single-pass membrane protein which functions as a glycosyltransferase. The encoded protein catalyzes the transfer of N-acetylglucosamine to glycosaminoglycan chains. This reaction is important in heparin and heparan sulfate synthesis. Alternative splicing results in the multiple transcript variants. [provided by RefSeq, Nov 2012], Cell Pathway/ Category Heparan sulfate biosynthesis, Protein Expression Amygdala,Brain,Fetus,Testis, Subcellular Localization endoplasmic reticulum,endoplasmic reticulum membrane,integral component of membrane, Protein Function catalytic activity:UDP-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan = UDP + alpha-N-acetyl-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan.,caution:It is uncertain whether Met-1, Met-6 or Met-20 is the initiator.,disease:Candidate gene for the breast cancer locus on chromosome 8p12-p22.,function:Probable glycosyltransferase.,online information:Exostosin-like 3,online information:GlycoGene database,pathway:Glycan metabolism; heparan sulfate biosynthesis.,similarity:Belongs to the glycosyltransferase 47 family.,tissue specificity:Ubiquitous., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | EXTL3 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | EXTL3 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | EXTL3 EXTL1L EXTR1 KIAA0519 |
| Accession No. | O43909 Q9WVL6 |
| Description | exostosin like glycosyltransferase 3(EXTL3) Homo sapiens This gene encodes a single-pass membrane protein which functions as a glycosyltransferase. The encoded protein catalyzes the transfer of N-acetylglucosamine to glycosaminoglycan chains. This reaction is important in heparin and heparan sulfate synthesis. Alternative splicing results in the multiple transcript variants. [provided by RefSeq, Nov 2012], |
| Cell Pathway/ Category | Heparan sulfate biosynthesis, |
| Protein Expression | Amygdala,Brain,Fetus,Testis, |
| Subcellular Localization | endoplasmic reticulum,endoplasmic reticulum membrane,integral component of membrane, |
| Protein Function | catalytic activity:UDP-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan = UDP + alpha-N-acetyl-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan.,caution:It is uncertain whether Met-1, Met-6 or Met-20 is the initiator.,disease:Candidate gene for the breast cancer locus on chromosome 8p12-p22.,function:Probable glycosyltransferase.,online information:Exostosin-like 3,online information:GlycoGene database,pathway:Glycan metabolism; heparan sulfate biosynthesis.,similarity:Belongs to the glycosyltransferase 47 family.,tissue specificity:Ubiquitous., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |