ITN2028
ITN2028
- Catalog: ITN2028
- Gene/Protein: PIGR
- Product Description: Immunotag™ PIGR Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | PIGR |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Rat,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | PIGR Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | PIGR |
| Accession No. | P01833 O70570 P15083 |
| Description | polymeric immunoglobulin receptor(PIGR) Homo sapiens This gene is a member of the immunoglobulin superfamily. The encoded poly-Ig receptor binds polymeric immunoglobulin molecules at the basolateral surface of epithelial cells; the complex is then transported across the cell to be secreted at the apical surface. A significant association was found between immunoglobulin A nephropathy and several SNPs in this gene.[provided by RefSeq, Sep 2009], |
| Cell Pathway/ Category | Intestinal immune network for IgA production, |
| Protein Expression | Bile,Liver,Milk,Plasma,Saliva,Small intestine, |
| Subcellular Localization | extracellular space,plasma membrane,integral component of plasma membrane,receptor complex,extracellular exosome, |
| Protein Function | function:This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment.,PTM:N-glycosylation is not necessary for Ig binding.,similarity:Contains 5 Ig-like V-type (immunoglobulin-like) domains., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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