ITN2094
ITN2094
- Catalog: ITN2094
- Gene/Protein: JAG2
- Product Description: Immunotag™ JAG2 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | JAG2 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from part region of human protein |
Specificity | JAG2 Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | JAG2 |
Accession No. | Q9Y219 Q9QYE5 P97607 |
Description | jagged 2(JAG2) Homo sapiens The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], |
Cell Pathway/ Category | Notch, |
Protein Expression | Bone marrow,Brain,Fetal brain,Heart, |
Subcellular Localization | plasma membrane,integral component of plasma membrane, |
Protein Function | disease:May be associated with Usher syndrome type IA (USHA1A) which describes a congenital sensory deafness associated with retinitis pigmentosa and feeble-mindedness.,function:Putative Notch ligand involved in the mediation of Notch signaling. Involved in limb development.,similarity:Contains 1 DSL domain.,similarity:Contains 1 VWFC domain.,similarity:Contains 16 EGF-like domains.,tissue specificity:Expressed in heart, placenta and skeletal muscle and to a lesser extend in pancreas. Very low expression in brain, lung, liver and kidney., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |