ITN2206
ITN2206
- Catalog: ITN2206
- Gene/Protein: PRDX6 AOP2 KIAA0106
- Product Description: Immunotag™ PRDX6 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | PRDX6 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Rat,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | PRDX6 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | PRDX6 AOP2 KIAA0106 |
| Accession No. | P30041 O08709 O35244 |
| Description | peroxiredoxin 6(PRDX6) Homo sapiens The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Phenylalanine metabolism,Methane metabolism, |
| Protein Expression | Bone marrow,Brain,Cajal-Retzius cell,Erythrocyte,Fetal brain,Fetal brain cortex,Liver,Plate |
| Subcellular Localization | extracellular space,cell,cytoplasm,lysosome,cytosol,cell-cell adherens junction,membrane,cytoplasmic, membrane-bounded vesicle,cytoplasmic vesicle,extracellular exosome, |
| Protein Function | catalytic activity:2 R'-SH + ROOH = R'-S-S-R' + H(2)O + ROH.,catalytic activity:Donor + H(2)O(2) = oxidized donor + 2 H(2)O.,function:Involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. May play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.,miscellaneous:Irreversibly inactivated by overoxidation of Cys-47 (to Cys-SO(3)H) upon oxidative stress.,miscellaneous:The active site is the redox-active Cys-47 oxidized to Cys-SOH. Cys-SOH may rapidly react with a Cys-SH of the other subunit to form an intermolecular disulfide with a concomitant homodimer formation. The enzyme may be subsequently regenerated by reduction of the disulfide by thioredoxin.,similarity:Belongs to the ahpC/TSA family. Rehydrin subfamily.,similarity:Contains 1 thioredoxin domain.,subcellular location:And also found in lung secretory organelles.,subunit:Homotetramer. May interact with HTR2A (By similarity). Interacts with STH., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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