ITN2211
ITN2211
- Catalog: ITN2211
- Gene/Protein: NR1D2
- Product Description: Immunotag™ NR1D2 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | NR1D2 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human,Rat,Mouse |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from part region of human protein |
Specificity | NR1D2 Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | NR1D2 |
Accession No. | Q14995 Q60674 Q63504 |
Description | nuclear receptor subfamily 1 group D member 2(NR1D2) Homo sapiens This gene encodes a member of the nuclear hormone receptor family, specifically the NR1 subfamily of receptors. The encoded protein functions as a transcriptional repressor and may play a role in circadian rhythms and carbohydrate and lipid metabolism. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009], |
Protein Expression | Brain,Hippocampus,Peripheral blood lymphocyte,Testis,Uterus |
Subcellular Localization | nucleus,nucleoplasm, |
Protein Function | function:Binds to the sequences 5'-AATGTAGGTCA-3' and 5'-ATAACTAGGTCA-3'. Acts as a potent competitive repressor of ROR alpha function.,similarity:Belongs to the nuclear hormone receptor family.,similarity:Belongs to the nuclear hormone receptor family. NR1 subfamily.,similarity:Contains 1 nuclear receptor DNA-binding domain.,subunit:Interacts with NCOA5 coactivator, leading to a strong increase of transcription of target genes., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |