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ITN2211

ITN2211
ITN2211
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$424.00
Price in reward points: 424
  • Catalog: ITN2211
  • Gene/Protein: NR1D2
  • Product Description: Immunotag™ NR1D2 Polyclonal Antibody

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Immunotag™ NR1D2 Polyclonal Antibody
Antibody Specification
Datasheet
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return.
Target Protein NR1D2
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000
Concentration 1 mg/ml
Reactive Species Human,Rat,Mouse
Host Species Rabbit
Immunogen Synthesized peptide derived from part region of human protein
Specificity NR1D2 Polyclonal Antibody detects endogenous levels of protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Gene Name NR1D2
Accession No. Q14995 Q60674 Q63504
Description nuclear receptor subfamily 1 group D member 2(NR1D2) Homo sapiens This gene encodes a member of the nuclear hormone receptor family, specifically the NR1 subfamily of receptors. The encoded protein functions as a transcriptional repressor and may play a role in circadian rhythms and carbohydrate and lipid metabolism. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009],
Protein Expression Brain,Hippocampus,Peripheral blood lymphocyte,Testis,Uterus
Subcellular Localization nucleus,nucleoplasm,
Protein Function function:Binds to the sequences 5'-AATGTAGGTCA-3' and 5'-ATAACTAGGTCA-3'. Acts as a potent competitive repressor of ROR alpha function.,similarity:Belongs to the nuclear hormone receptor family.,similarity:Belongs to the nuclear hormone receptor family. NR1 subfamily.,similarity:Contains 1 nuclear receptor DNA-binding domain.,subunit:Interacts with NCOA5 coactivator, leading to a strong increase of transcription of target genes.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.

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