ITN2237
ITN2237
ITN2237
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$424.00
Price in reward points: 424
- Catalog: ITN2237
- Gene/Protein: RAP1B OK/SW-cl.11
- Product Description: Immunotag™ RAP1B Polyclonal Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein RAP1B Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,ELISA Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000 Concentration 1 mg/ml Reactive Species Human,Rat,Mouse Host Species Rabbit Immunogen Synthesized peptide derived from human protein, at AA range: 110-190 Specificity RAP1B Polyclonal Antibody detects endogenous levels of protein. Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. Gene Name RAP1B OK/SW-cl.11 Accession No. P61224 Q99JI6 Q62636 Description RAP1B, member of RAS oncogene family(RAP1B) Homo sapiens This gene encodes a member of the RAS-like small GTP-binding protein superfamily. Members of this family regulate multiple cellular processes including cell adhesion and growth and differentiation. This protein localizes to cellular membranes and has been shown to regulate integrin-mediated cell signaling. This protein also plays a role in regulating outside-in signaling in platelets. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 5, 6 and 9. [provided by RefSeq, Oct 2011], Cell Pathway/ Category MAPK_ERK_Growth,MAPK_G_Protein,Chemokine,Focal adhesion,Leukocyte transendothelial migration,Long-term potentiation,Neurotrophin,Renal cell carcinoma, Protein Expression Amygdala,Brain,Chondrosarcoma,Colon adenocarcinoma,Placenta,Platele Subcellular Localization intracellular,lipid particle,cytosol,plasma membrane,cell-cell junction,membrane,membrane raft,extracellular exosome, Protein Function enzyme regulation:Activated by guanine nucleotide-exchange factor (GEF) EPAC2 in a cAMP-dependent manner.,similarity:Belongs to the small GTPase superfamily. Ras family.,subcellular location:May shuttle between plasma membrane and cytosol.,subunit:Interacts with SGSM1, SGSM2 and SGSM3., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | RAP1B |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Rat,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein, at AA range: 110-190 |
| Specificity | RAP1B Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | RAP1B OK/SW-cl.11 |
| Accession No. | P61224 Q99JI6 Q62636 |
| Description | RAP1B, member of RAS oncogene family(RAP1B) Homo sapiens This gene encodes a member of the RAS-like small GTP-binding protein superfamily. Members of this family regulate multiple cellular processes including cell adhesion and growth and differentiation. This protein localizes to cellular membranes and has been shown to regulate integrin-mediated cell signaling. This protein also plays a role in regulating outside-in signaling in platelets. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 5, 6 and 9. [provided by RefSeq, Oct 2011], |
| Cell Pathway/ Category | MAPK_ERK_Growth,MAPK_G_Protein,Chemokine,Focal adhesion,Leukocyte transendothelial migration,Long-term potentiation,Neurotrophin,Renal cell carcinoma, |
| Protein Expression | Amygdala,Brain,Chondrosarcoma,Colon adenocarcinoma,Placenta,Platele |
| Subcellular Localization | intracellular,lipid particle,cytosol,plasma membrane,cell-cell junction,membrane,membrane raft,extracellular exosome, |
| Protein Function | enzyme regulation:Activated by guanine nucleotide-exchange factor (GEF) EPAC2 in a cAMP-dependent manner.,similarity:Belongs to the small GTPase superfamily. Ras family.,subcellular location:May shuttle between plasma membrane and cytosol.,subunit:Interacts with SGSM1, SGSM2 and SGSM3., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |