ITN2309
ITN2309
- Catalog: ITN2309
- Gene/Protein: SLC18A2 SVMT VMAT2
- Product Description: Immunotag™ VMAT2 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
|
| Target Protein | VMAT2 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Rat,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein, at AA range: 1-80 |
| Specificity | VMAT2 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | SLC18A2 SVMT VMAT2 |
| Accession No. | Q05940 Q8BRU6 Q01827 |
| Description | solute carrier family 18 member A2(SLC18A2) Homo sapiens The vesicular monoamine transporter acts to accumulate cytosolic monoamines into synaptic vesicles, using the proton gradient maintained across the synaptic vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (summary by Peter et al., 1993 [PubMed 7905859]). See also SLC18A1 (MIM 193002).[supplied by OMIM, Jan 2011], |
| Cell Pathway/ Category | Parkinson's disease, |
| Protein Expression | Brain,Platelet,Substantia nigra,Testis, |
| Subcellular Localization | plasma membrane,integral component of plasma membrane,synaptic vesicle,membrane,synaptic vesicle membrane,terminal bouton,clathrin-sculpted monoamine transport vesicle membrane, |
| Protein Function | function:Involved in the ATP-dependent vesicular transport of biogenic amine neurotransmitters. Pumps cytosolic monoamines including dopamine, norepinephrine, serotonin, and histamine into synaptic vesicles. Requisite for vesicular amine storage prior to secretion via exocytosis.,online information:Vesicular monoamine transporter entry,similarity:Belongs to the major facilitator superfamily. Vesicular transporter family., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
| English_US |
|
| Danish |
|
| Dutch |
|
| English_UK |
|
| French |
|
| German |
|
| Spanish |
|
| Norwegian |
|
| Portuguese |
|
| Finnish |
|
| Swedish |
|
| Polish |
|