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ITN2337

ITN2337
  • Catalog: ITN2337
  • Gene/Protein: NR4A2 NOT NURR1 TINUR
  • Product Description: Immunotag™ NR4A2 Polyclonal Antibody
385.0000
Price in reward points: 385

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Immunotag™ NR4A2 Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein NR4A2
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000
Concentration 1 mg/ml
Reactive Species Human,Mouse,Rat
Host Species Rabbit
Immunogen Synthesized peptide derived from human protein, at AA range: 100-180
Specificity NR4A2 Polyclonal Antibody detects endogenous levels of protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Gene Name NR4A2 NOT NURR1 TINUR
Accession No. P43354 Q06219 Q07917
Description nuclear receptor subfamily 4 group A member 2(NR4A2) Homo sapiens This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008],
Protein Expression Blood,Brain,Epithelium,Fibroblast,Skin,Spleen,Testis,
Subcellular Localization nucleus,nucleoplasm,cytoplasm,
Protein Function developmental stage:Rapidly and only very transiently expressed after cell activation, during the G0-G1 transition of the cell cycle.,function:Probable nuclear receptor. May function as a general coactivator of gene transcription. Detection of the protein in the brain, indicates that it is not mandatorily associated with cell cycle progression.,similarity:Belongs to the nuclear hormone receptor family.,similarity:Belongs to the nuclear hormone receptor family. NR4 subfamily.,similarity:Contains 1 nuclear receptor DNA-binding domain.,tissue specificity:Expressed in a number of cell lines of T-cell, B-cell and fibroblast origin. Strong expression in brain tissue.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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