ITN2424
ITN2424
- Catalog: ITN2424
- Gene/Protein: FXYD5 DYSAD IWU1 HSPC113 UNQ2561/PRO6241
- Product Description: Immunotag™ FXYD5 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | FXYD5 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein, at AA range: Internal |
| Specificity | FXYD5 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | FXYD5 DYSAD IWU1 HSPC113 UNQ2561/PRO6241 |
| Accession No. | Q96DB9 P97808 P59647 |
| Description | FXYD domain containing ion transport regulator 5(FXYD5) Homo sapiens This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. This gene product, FXYD5, is a glycoprotein that functions in the up |
| Protein Expression | Bone marrow,Leukocyte,Pancreas,Umbilical cord blood, |
| Subcellular Localization | integral component of plasma membrane,membrane,integral component of membrane, |
| Protein Function | function:Involved in down-regulation of E-cadherin which results in reduced cell adhesion. Promotes metastasis.,PTM:Glycosylated.,similarity:Belongs to the FXYD family., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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