ITN2455
ITN2455
ITN2455
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- Catalog: ITN2455
- Gene/Protein: TRIP6 OIP1
- Product Description: Immunotag™ TRIP6 Polyclonal Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein TRIP6 Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,ELISA Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000 Concentration 1 mg/ml Reactive Species Human Host Species Rabbit Immunogen Synthesized peptide derived from human protein . at AA range: 221-270 Specificity TRIP6 Polyclonal Antibody detects endogenous levels of protein. Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. Gene Name TRIP6 OIP1 Accession No. Q15654 Q9Z1Y4 Description thyroid hormone receptor interactor 6(TRIP6) Homo sapiens This gene is a member of the zyxin family and encodes a protein with three LIM zinc-binding domains. This protein localizes to focal adhesion sites and along actin stress fibers. Recruitment of this protein to the plasma membrane occurs in a lysophosphatidic acid (LPA)-dependent manner and it regulates LPA-induced cell migration. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008], Cell Pathway/ Category NOD-like receptor, Protein Expression Cervix,Epithelium,Kidney,Pancreas,Salivary gland, Subcellular Localization nucleus,cytoplasm,cytoskeleton,plasma membrane,focal adhesion,interleukin-1 receptor complex, Protein Function function:May relays signals from the cell surface to the nucleus.,similarity:Belongs to the zyxin/ajuba family.,similarity:Contains 1 LIM zinc-binding domain.,similarity:Contains 3 LIM zinc-binding domains.,subunit:Specifically interacts with the ligand binding domain of the thyroid receptor (TR). Requires the presence of thyroid hormone for its interaction. Interacts with PTPN13.,tissue specificity:Abundantly expressed in kidney, liver and lung. Lower levels in heart, placenta and pancreas., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | TRIP6 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 221-270 |
| Specificity | TRIP6 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | TRIP6 OIP1 |
| Accession No. | Q15654 Q9Z1Y4 |
| Description | thyroid hormone receptor interactor 6(TRIP6) Homo sapiens This gene is a member of the zyxin family and encodes a protein with three LIM zinc-binding domains. This protein localizes to focal adhesion sites and along actin stress fibers. Recruitment of this protein to the plasma membrane occurs in a lysophosphatidic acid (LPA)-dependent manner and it regulates LPA-induced cell migration. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | NOD-like receptor, |
| Protein Expression | Cervix,Epithelium,Kidney,Pancreas,Salivary gland, |
| Subcellular Localization | nucleus,cytoplasm,cytoskeleton,plasma membrane,focal adhesion,interleukin-1 receptor complex, |
| Protein Function | function:May relays signals from the cell surface to the nucleus.,similarity:Belongs to the zyxin/ajuba family.,similarity:Contains 1 LIM zinc-binding domain.,similarity:Contains 3 LIM zinc-binding domains.,subunit:Specifically interacts with the ligand binding domain of the thyroid receptor (TR). Requires the presence of thyroid hormone for its interaction. Interacts with PTPN13.,tissue specificity:Abundantly expressed in kidney, liver and lung. Lower levels in heart, placenta and pancreas., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |