ITN2501
ITN2501
ITN2501
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- Catalog: ITN2501
- Gene/Protein: ZC3HAV1 ZC3HDC2 PRO1677
- Product Description: Immunotag™ ZCCHV Polyclonal Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein ZCCHV Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,ELISA Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000 Concentration 1 mg/ml Reactive Species Human Host Species Rabbit Immunogen Synthesized peptide derived from human protein, at AA range: 211-260 Specificity ZCCHV Polyclonal Antibody detects endogenous levels of protein. Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. Gene Name ZC3HAV1 ZC3HDC2 PRO1677 Accession No. Q7Z2W4 Q3UPF5 Q8K3Y6 Description zinc finger CCCH-type containing, antiviral 1(ZC3HAV1) Homo sapiens This gene encodes a CCCH-type zinc finger protein that is thought to prevent infection by retroviruses. Studies of the rat homolog indicate that the protein may primarily function to inhibit viral gene expression and induce an innate immunity to viral infection. Alternative splicing occurs at this locus and two variants, each encoding distinct isoforms, are described. [provided by RefSeq, Jul 2008], Protein Expression Brain,Endometrium,Epithelium,Fetal liver,Kidney,Ovarian car Subcellular Localization nucleus,cytoplasm,lysosome,late endosome,Golgi apparatus,cell-cell adherens junction, Protein Function domain:The second and fourth zinc fingers are involved in binding to specific viral RNAs.,function:Induces an innate immunity to viral infections by preventing the accumulation of viral RNAs in the cytoplasm. Seems to recruit the RNA processing exosome to degrade the target RNAs. Inhibits alphavirus and filovirus replication.,similarity:Contains 1 PARP catalytic domain.,similarity:Contains 1 WWE domain.,similarity:Contains 4 C3H1-type zinc fingers.,subcellular location:Localizes in the cytoplasm at steady state, but shuttles between nucleus and cytoplasm in a XPO1-dependent manner.,subunit:Interacts with EXOSC5., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | ZCCHV |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein, at AA range: 211-260 |
| Specificity | ZCCHV Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | ZC3HAV1 ZC3HDC2 PRO1677 |
| Accession No. | Q7Z2W4 Q3UPF5 Q8K3Y6 |
| Description | zinc finger CCCH-type containing, antiviral 1(ZC3HAV1) Homo sapiens This gene encodes a CCCH-type zinc finger protein that is thought to prevent infection by retroviruses. Studies of the rat homolog indicate that the protein may primarily function to inhibit viral gene expression and induce an innate immunity to viral infection. Alternative splicing occurs at this locus and two variants, each encoding distinct isoforms, are described. [provided by RefSeq, Jul 2008], |
| Protein Expression | Brain,Endometrium,Epithelium,Fetal liver,Kidney,Ovarian car |
| Subcellular Localization | nucleus,cytoplasm,lysosome,late endosome,Golgi apparatus,cell-cell adherens junction, |
| Protein Function | domain:The second and fourth zinc fingers are involved in binding to specific viral RNAs.,function:Induces an innate immunity to viral infections by preventing the accumulation of viral RNAs in the cytoplasm. Seems to recruit the RNA processing exosome to degrade the target RNAs. Inhibits alphavirus and filovirus replication.,similarity:Contains 1 PARP catalytic domain.,similarity:Contains 1 WWE domain.,similarity:Contains 4 C3H1-type zinc fingers.,subcellular location:Localizes in the cytoplasm at steady state, but shuttles between nucleus and cytoplasm in a XPO1-dependent manner.,subunit:Interacts with EXOSC5., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |