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ITN2501

  • Gene/Protein: ZC3HAV1 ZC3HDC2 PRO1677
  • Product Description: Immunotag™ ZCCHV Polyclonal Antibody
  • 280.0000
    Price in reward points: 294

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ITN2501

Immunotag™ ZCCHV Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein ZCCHV
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000
Concentration 1 mg/ml
Reactive Species Human
Host Species Rabbit
Immunogen Synthesized peptide derived from human protein, at AA range: 211-260
Specificity ZCCHV Polyclonal Antibody detects endogenous levels of protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Gene Name ZC3HAV1 ZC3HDC2 PRO1677
Accession No. Q7Z2W4 Q3UPF5 Q8K3Y6
Description zinc finger CCCH-type containing, antiviral 1(ZC3HAV1) Homo sapiens This gene encodes a CCCH-type zinc finger protein that is thought to prevent infection by retroviruses. Studies of the rat homolog indicate that the protein may primarily function to inhibit viral gene expression and induce an innate immunity to viral infection. Alternative splicing occurs at this locus and two variants, each encoding distinct isoforms, are described. [provided by RefSeq, Jul 2008],
Protein Expression Brain,Endometrium,Epithelium,Fetal liver,Kidney,Ovarian car
Subcellular Localization nucleus,cytoplasm,lysosome,late endosome,Golgi apparatus,cell-cell adherens junction,
Protein Function domain:The second and fourth zinc fingers are involved in binding to specific viral RNAs.,function:Induces an innate immunity to viral infections by preventing the accumulation of viral RNAs in the cytoplasm. Seems to recruit the RNA processing exosome to degrade the target RNAs. Inhibits alphavirus and filovirus replication.,similarity:Contains 1 PARP catalytic domain.,similarity:Contains 1 WWE domain.,similarity:Contains 4 C3H1-type zinc fingers.,subcellular location:Localizes in the cytoplasm at steady state, but shuttles between nucleus and cytoplasm in a XPO1-dependent manner.,subunit:Interacts with EXOSC5.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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