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ITN2503

ITN2503
ITN2503
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$424.00
Price in reward points: 424
  • Catalog: ITN2503
  • Gene/Protein: DEFA6 DEF6
  • Product Description: Immunotag™ DEF6 Polyclonal Antibody

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Immunotag™ DEF6 Polyclonal Antibody
Antibody Specification
Datasheet
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return.
Target Protein DEF6
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000
Concentration 1 mg/ml
Reactive Species Human
Host Species Rabbit
Immunogen Synthesized peptide derived from human protein . at AA range: 51-100
Specificity DEF6 Polyclonal Antibody detects endogenous levels of protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Gene Name DEFA6 DEF6
Accession No. Q01524
Description defensin alpha 6(DEFA6) Homo sapiens Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 6, is highly expressed in the secretory granules of Paneth cells of the small intestine, and likely plays a role in host defense of human bowel. [provided by RefSeq, Oct 2014],
Protein Expression Brain,Intestine,
Subcellular Localization extracellular region,extracellular space,Golgi lumen,
Protein Function function:Has very low antimicrobial activity against Gram-negative and Gram-positive bacteria. May protect cells against infection with HIV-1.,similarity:Belongs to the alpha-defensin family.,subunit:Homodimer.,tissue specificity:Paneth cells of the small intestine.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.

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