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ITN2692

ITN2692
  • Catalog: ITN2692
  • Gene/Protein: TBXA2R
  • Product Description: Immunotag™ TA2R Polyclonal Antibody
385.0000
Price in reward points: 385

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Immunotag™ TA2R Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein TA2R
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000
Concentration 1 mg/ml
Reactive Species Human,Rat,Mouse
Host Species Rabbit
Immunogen Synthesized peptide derived from human protein, at AA range: 230-310
Specificity TA2R Polyclonal Antibody detects endogenous levels of protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Gene Name TBXA2R
Accession No. P21731 P30987 P34978
Description thromboxane A2 receptor(TBXA2R) Homo sapiens This gene encodes a member of the G protein-coupled receptor family. The protein interacts with thromboxane A2 to induce platelet aggregation and regulate hemostasis. A mutation in this gene results in a bleeding disorder. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009],
Cell Pathway/ Category Calcium,Neuroactive ligand-receptor interaction,
Protein Expression Blood,Endothelial cell,Lung,PCR rescued clones,Placenta,Platelet,
Subcellular Localization acrosomal vesicle,plasma membrane,integral component of plasma membrane,integral component of membrane,
Protein Function disease:Defects in TBXA2R are the cause of a dominantly inherited bleeding disorder [MIM:188070].,function:Receptor for thromboxane A2 (TXA2), a potent stimulator of platelet aggregation. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. In the kidney, the binding of TXA2 to glomerular TP receptors causes intense vasoconstriction. Activates phospholipase C. Isoform 1 activates adenylyl cyclase, isoform 2 inhibits adenylyl cyclase.,similarity:Belongs to the G-protein coupled receptor 1 family.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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