ITN2713
ITN2713
- Catalog: ITN2713
- Gene/Protein: NPFFR2 GPR74 NPFF2 NPGPR
- Product Description: Immunotag™ NPFF2 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | NPFF2 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Rat,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein, at AA range: 10-90 |
| Specificity | NPFF2 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | NPFFR2 GPR74 NPFF2 NPGPR |
| Accession No. | Q9Y5X5 Q924H0 Q9EQD2 |
| Description | neuropeptide FF receptor 2(NPFFR2) Homo sapiens This gene encodes a member of a subfamily of G-protein-coupled neuropeptide receptors. This protein is activated by the neuropeptides A-18-amide (NPAF) and F-8-amide (NPFF) and may function in pain modulation and regulation of the opioid system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009], |
| Cell Pathway/ Category | Neuroactive ligand-receptor interaction, |
| Protein Expression | Brain,Fetus,Lung and placenta,Spinal cord, |
| Subcellular Localization | plasma membrane,integral component of plasma membrane,actin cytoskeleton,integral component of membrane, |
| Protein Function | Experimental confirmation may be lacking for some isoforms,function:Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Isoform 1 is abundant in placenta. Relatively highly expressed in thymus, testis, and small intestine. Expressed at low levels in several tissues including spleen, prostate, brain, heart, ovary, colon, kidney, lung, liver and pancreas and not expressed in skeletal muscle and leukocytes. Highest but relatively low level of isoform 2 in placenta and very low level in numerous tissues including adipose tissue and many brain regions. Isoform 3 is expressed in brain and heart and, at lower levels, in kidney, liver, lung and pancreas., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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