ITN2742
ITN2742
- Catalog: ITN2742
- Gene/Protein: OPN1MW GCP; OPN1MW2
- Product Description: Immunotag™ OPSG Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | OPSG |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human,Rat,Mouse |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from human protein, at AA range: 200-280 |
Specificity | OPSG Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | OPN1MW GCP; OPN1MW2 |
Accession No. | P04001 O35599 O35476 |
Description | opsin 1 (cone pigments), medium-wave-sensitive(OPN1MW) Homo sapiens This gene encodes for a light absorbing visual pigment of the opsin gene family. The encoded protein is called green cone photopigment or medium-wavelength sensitive opsin. Opsins are G-protein coupled receptors with seven transmembrane domains, an N-terminal extracellular domain, and a C-terminal cytoplasmic domain. The long-wavelength opsin gene and multiple copies of the medium-wavelength opsin gene are tandemly arrayed on the X chromosome and frequent unequal recombination and gene conversion may occur between these sequences. X chromosomes may have fusions of the medium- and long-wavelength opsin genes or may have more than one copy of these genes. Defects in this gene are the cause of deutanopic colorblindness. [provided by RefSeq, Mar 2009], |
Protein Expression | Retinal cone cell, |
Subcellular Localization | photoreceptor outer segment,plasma membrane,integral component of plasma membrane,integral component of membrane,photoreceptor outer segment membrane, |
Protein Function | disease:Defects in OPN1MW are the cause of partial colorblindness deutan series (CBD) [MIM:303800]; also called deuteranopia.,function:Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal.,online information:Retina International's Scientific Newsletter,PTM:Phosphorylated on some or all of the serine and threonine residues present in the C-terminal region.,similarity:Belongs to the G-protein coupled receptor 1 family.,similarity:Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.,tissue specificity:The three color pigments are found in the cone photoreceptor cells., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |