ITN2951
ITN2951
ITN2951
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- Catalog: ITN2951
- Gene/Protein: MAPRE3
- Product Description: Immunotag™ MARE3 Polyclonal Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein MARE3 Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,ELISA Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000 Concentration 1 mg/ml Reactive Species Human,Mouse,Rat Host Species Rabbit Immunogen Synthesized peptide derived from part region of human protein Specificity MARE3 Polyclonal Antibody detects endogenous levels of protein. Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. Gene Name MAPRE3 Accession No. Q9UPY8 Q6PER3 Q5XIT1 Description microtubule associated protein RP/EB family member 3(MAPRE3) Homo sapiens The protein encoded by this gene is a member of the RP/EB family of genes. The protein localizes to the cytoplasmic microtubule network and binds APCL, a homolog of the adenomatous polyposis coli tumor suppressor gene. [provided by RefSeq, Jul 2008], Protein Expression Fetal brain,Kidney, Subcellular Localization cytoplasm,microtubule cytoskeleton,midbody,microtubule plus-end,perinuclear region of cytoplasm, Protein Function domain:Composed of two functionally independent domains. The N-terminal domain forms an hydrophobic cleft involved in microtubule binding and the C-terminal is involved in the formation of mutually exclusive complexes with APC and DCTN1.,function:May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration.,similarity:Belongs to the MAPRE family.,similarity:Contains 1 CH (calponin-homology) domain.,similarity:Contains 1 EB1 C-terminal domain.,subcellular location:Associated with the microtubule network.,subunit:Interacts with APC2 (By similarity). Interacts with DCTN1. Binds to the C-terminal domain of APC. Binds monomeric and polymerized tubulin.,tissue specificity:Predominantly expressed in brain and muscle., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | MARE3 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | MARE3 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | MAPRE3 |
| Accession No. | Q9UPY8 Q6PER3 Q5XIT1 |
| Description | microtubule associated protein RP/EB family member 3(MAPRE3) Homo sapiens The protein encoded by this gene is a member of the RP/EB family of genes. The protein localizes to the cytoplasmic microtubule network and binds APCL, a homolog of the adenomatous polyposis coli tumor suppressor gene. [provided by RefSeq, Jul 2008], |
| Protein Expression | Fetal brain,Kidney, |
| Subcellular Localization | cytoplasm,microtubule cytoskeleton,midbody,microtubule plus-end,perinuclear region of cytoplasm, |
| Protein Function | domain:Composed of two functionally independent domains. The N-terminal domain forms an hydrophobic cleft involved in microtubule binding and the C-terminal is involved in the formation of mutually exclusive complexes with APC and DCTN1.,function:May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration.,similarity:Belongs to the MAPRE family.,similarity:Contains 1 CH (calponin-homology) domain.,similarity:Contains 1 EB1 C-terminal domain.,subcellular location:Associated with the microtubule network.,subunit:Interacts with APC2 (By similarity). Interacts with DCTN1. Binds to the C-terminal domain of APC. Binds monomeric and polymerized tubulin.,tissue specificity:Predominantly expressed in brain and muscle., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |