ITN3006
ITN3006
- Catalog: ITN3006
- Gene/Protein: MDH1 MDHA
- Product Description: Immunotag™ MDHC Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | MDHC |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | MDHC Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | MDH1 MDHA |
| Accession No. | P40925 P14152 O88989 |
| Description | malate dehydrogenase 1(MDH1) Homo sapiens This gene encodes an enzyme that catalyzes the NAD/NADH-dependent, reversible oxidation of malate to oxaloacetate in many metabolic pathways, including the citric acid cycle. Two main isozymes are known to exist in eukaryotic cells: one is found in the mitochondrial matrix and the other in the cytoplasm. This gene encodes the cytosolic isozyme, which plays a key role in the malate-aspartate shuttle that allows malate to pass through the mitochondrial membrane to be transformed into oxaloacetate for further cellular processes. Alternatively spliced transcript variants have been found for this gene. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Pseudogenes have been identified on chromosomes X and 6. [provided by RefSeq, |
| Cell Pathway/ Category | Citrate cycle (TCA cycle),Pyruvate metabolism,Glyoxylate and dicarboxylate metabolism, |
| Protein Expression | Brain,Cajal-Retzius cell,Heart,Placenta,T-cell, |
| Subcellular Localization | extracellular space,cytoplasm,mitochondrion,centrosome,cytosol,myelin sheath,extracellular exosome, |
| Protein Function | catalytic activity:(S)-malate + NAD(+) = oxaloacetate + NADH.,online information:Malate dehydrogenase entry,similarity:Belongs to the LDH/MDH superfamily. MDH type 2 family.,subunit:Homodimer., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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