ITP0830
ITP0830
ITP0830
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$541.00
Price in reward points: 541
- Catalog: ITP0830
- Gene/Protein: PPP1R2
- Product Description: Immunotag™ IPP-2 (phospho Ser44) Polyclonal Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein IPP-2 (Ser44) Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,IHC-p,ELISA Recommended Dilution Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. Concentration 1 mg/ml Reactive Species Human,Mouse,Rat Host Species Rabbit Immunogen Synthesized phospho-peptide around the phosphorylation site of human IPP-2 (phospho Ser44) Specificity Phospho-IPP-2 (S44) Polyclonal Antibody detects endogenous levels of IPP-2 protein only when phosphorylated at S44. Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Gene Name PPP1R2 Accession No. P41236 Q9DCL8 P50411 Alternate Names PPP1R2; IPP2; Protein phosphatase inhibitor 2; IPP-2 Description protein phosphatase 1 regulatory inhibitor subunit 2(PPP1R2) Homo sapiens Protein phosphatase-1 (PP1) is one of the main eukaryotic serine/threonine phosphatases. The protein encoded by this gene binds to the catalytic subunit of PP1, strongly inhibiting its activity. Ten related pseudogenes have been found throughout the human genome. Several splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015], Protein Expression Epithelium,Heart,Platelet,Skin,Testis, Subcellular Localization protein phosphatase type 1 complex, Protein Function function:Inhibitor of protein-phosphatase 1.,PTM:Phosphorylation on Thr-73 by GSK3 activates PP1 by dissociating the PP1-PPP1R2 complex (By similarity). Phosphorylation on Ser-44 by ATM activates PP1 by dissociating the PP1-PPP1R2 complex.,similarity:Belongs to the protein phosphatase inhibitor 2 family.,subunit:Heterodimer with PP1., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | IPP-2 (Ser44) |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized phospho-peptide around the phosphorylation site of human IPP-2 (phospho Ser44) |
| Specificity | Phospho-IPP-2 (S44) Polyclonal Antibody detects endogenous levels of IPP-2 protein only when phosphorylated at S44. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | PPP1R2 |
| Accession No. | P41236 Q9DCL8 P50411 |
| Alternate Names | PPP1R2; IPP2; Protein phosphatase inhibitor 2; IPP-2 |
| Description | protein phosphatase 1 regulatory inhibitor subunit 2(PPP1R2) Homo sapiens Protein phosphatase-1 (PP1) is one of the main eukaryotic serine/threonine phosphatases. The protein encoded by this gene binds to the catalytic subunit of PP1, strongly inhibiting its activity. Ten related pseudogenes have been found throughout the human genome. Several splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015], |
| Protein Expression | Epithelium,Heart,Platelet,Skin,Testis, |
| Subcellular Localization | protein phosphatase type 1 complex, |
| Protein Function | function:Inhibitor of protein-phosphatase 1.,PTM:Phosphorylation on Thr-73 by GSK3 activates PP1 by dissociating the PP1-PPP1R2 complex (By similarity). Phosphorylation on Ser-44 by ATM activates PP1 by dissociating the PP1-PPP1R2 complex.,similarity:Belongs to the protein phosphatase inhibitor 2 family.,subunit:Heterodimer with PP1., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |