ITP0891
ITP0891
ITP0891
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$541.00
Price in reward points: 541
- Catalog: ITP0891
- Gene/Protein: RPH3A
- Product Description: Immunotag™ Rabphilin-3A (phospho Ser237) Polyclonal Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein RabphIL-in-3A (Ser237) Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,IHC-p,IF,ELISA Recommended Dilution Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. Concentration 1 mg/ml Reactive Species Human,Mouse,Rat Host Species Rabbit Immunogen Synthesized phospho-peptide around the phosphorylation site of human Rabphilin-3A (phospho Ser237) Specificity Phospho-Rabphilin-3A (S237) Polyclonal Antibody detects endogenous levels of Rabphilin-3A protein only when phosphorylated at S237. Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Gene Name RPH3A Accession No. Q9Y2J0 P47708 P47709 Alternate Names RPH3A; KIAA0985; Rabphilin-3A; Exophilin-1 Description rabphilin 3A(RPH3A) Homo sapiens Exocytosis of neurotransmitters and hormones is fundamental to synaptic neurotransmission and cell-cell communication. RAB3A (MIM 179390) is a small G protein that is thought to act at late stages of exocytosis, and RPH3A is a RAB3A effector (Lin et al., 2007 [PubMed 17149709]).[supplied by OMIM, Jul 2008], Protein Expression Brain,Lung, Subcellular Localization intracellular,Golgi apparatus,cytosol,plasma membrane,synaptic vesicle,membrane,extrinsic component of membrane,cell junction,secretory granule,synaptic vesicle membrane,neuron projection,protein complex,synapse, Protein Function function:Protein transport. Probably involved with Ras-related protein Rab-3A in synaptic vesicle traffic and/or synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal.,similarity:Contains 1 FYVE-type zinc finger.,similarity:Contains 1 RabBD (Rab-binding) domain.,similarity:Contains 2 C2 domains., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | RabphIL-in-3A (Ser237) |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,IF,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized phospho-peptide around the phosphorylation site of human Rabphilin-3A (phospho Ser237) |
| Specificity | Phospho-Rabphilin-3A (S237) Polyclonal Antibody detects endogenous levels of Rabphilin-3A protein only when phosphorylated at S237. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | RPH3A |
| Accession No. | Q9Y2J0 P47708 P47709 |
| Alternate Names | RPH3A; KIAA0985; Rabphilin-3A; Exophilin-1 |
| Description | rabphilin 3A(RPH3A) Homo sapiens Exocytosis of neurotransmitters and hormones is fundamental to synaptic neurotransmission and cell-cell communication. RAB3A (MIM 179390) is a small G protein that is thought to act at late stages of exocytosis, and RPH3A is a RAB3A effector (Lin et al., 2007 [PubMed 17149709]).[supplied by OMIM, Jul 2008], |
| Protein Expression | Brain,Lung, |
| Subcellular Localization | intracellular,Golgi apparatus,cytosol,plasma membrane,synaptic vesicle,membrane,extrinsic component of membrane,cell junction,secretory granule,synaptic vesicle membrane,neuron projection,protein complex,synapse, |
| Protein Function | function:Protein transport. Probably involved with Ras-related protein Rab-3A in synaptic vesicle traffic and/or synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal.,similarity:Contains 1 FYVE-type zinc finger.,similarity:Contains 1 RabBD (Rab-binding) domain.,similarity:Contains 2 C2 domains., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |