ITT0051
ITT0051
ITT0051
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$424.00
Price in reward points: 424
- Catalog: ITT0051
- Gene/Protein: ABCF1
- Product Description: Immunotag™ ABCF1 Polyclonal Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein ABCF1 Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,ELISA Recommended Dilution Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. Concentration 1 mg/ml Reactive Species Human,Mouse,Rat Host Species Rabbit Immunogen Synthesized peptide derived from ABCF1, at AA range: 760-840 Specificity ABCF1 Polyclonal Antibody detects endogenous levels of ABCF1 protein. Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Gene Name ABCF1 Accession No. Q8NE71 Q6P542 Q6MG08 Alternate Names ABCF1; ABC50; ATP-binding cassette sub-family F member 1; ATP-binding cassette 50; TNF-alpha-stimulated ABC protein Description ATP binding cassette subfamily F member 1(ABCF1) Homo sapiens The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the GCN20 subfamily. Unlike other members of the superfamily, this protein lacks the transmembrane domains which are characteristic of most ABC transporters. This protein may be regulated by tumor necrosis factor-alpha and play a role in enhancement of protein synthesis and the inflammation process. [provided by RefSeq, Jul 2008], Protein Expression Brain,Embryonic stem cells,Epithelium,Liver,Melanoma,Periph Subcellular Localization nuclear envelope,nucleoplasm,cytoplasm,cytosol,ribosome,membrane,polysomal ribosome, Protein Function function:May function in mRNA translation.,induction:By TNF (in cultured synoviocytes).,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the ABC transporter family.,similarity:Belongs to the ABC transporter family. EF3 subfamily.,similarity:Contains 2 ABC transporter domains.,subunit:Interacts with eukaryotic initiation factor 2 (eIF2). Associates with the ribosomes.,tissue specificity:Ubiquitous., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | ABCF1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from ABCF1, at AA range: 760-840 |
| Specificity | ABCF1 Polyclonal Antibody detects endogenous levels of ABCF1 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | ABCF1 |
| Accession No. | Q8NE71 Q6P542 Q6MG08 |
| Alternate Names | ABCF1; ABC50; ATP-binding cassette sub-family F member 1; ATP-binding cassette 50; TNF-alpha-stimulated ABC protein |
| Description | ATP binding cassette subfamily F member 1(ABCF1) Homo sapiens The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the GCN20 subfamily. Unlike other members of the superfamily, this protein lacks the transmembrane domains which are characteristic of most ABC transporters. This protein may be regulated by tumor necrosis factor-alpha and play a role in enhancement of protein synthesis and the inflammation process. [provided by RefSeq, Jul 2008], |
| Protein Expression | Brain,Embryonic stem cells,Epithelium,Liver,Melanoma,Periph |
| Subcellular Localization | nuclear envelope,nucleoplasm,cytoplasm,cytosol,ribosome,membrane,polysomal ribosome, |
| Protein Function | function:May function in mRNA translation.,induction:By TNF (in cultured synoviocytes).,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the ABC transporter family.,similarity:Belongs to the ABC transporter family. EF3 subfamily.,similarity:Contains 2 ABC transporter domains.,subunit:Interacts with eukaryotic initiation factor 2 (eIF2). Associates with the ribosomes.,tissue specificity:Ubiquitous., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |