ITT0514
ITT0514
ITT0514
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$424.00
Price in reward points: 424
- Catalog: ITT0514
- Gene/Protein: BDKRB1
- Product Description: Immunotag™ Bradykinin B1 R Polyclonal Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein Bradykinin B1 R Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,IF,ELISA Recommended Dilution Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications. Concentration 1 mg/ml Reactive Species Human Host Species Rabbit Immunogen The antiserum was produced against synthesized peptide derived from human BDKRB1. AA range:201-250 Specificity Bradykinin B1 R Polyclonal Antibody detects endogenous levels of Bradykinin B1 R protein. Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Gene Name BDKRB1 Accession No. P46663 Q61125 Alternate Names BDKRB1; BRADYB1; B1 bradykinin receptor; B1R; BK-1 receptor Description bradykinin receptor B1(BDKRB1) Homo sapiens Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011], Cell Pathway/ Category Calcium,Neuroactive ligand-receptor interaction,Complement and coagulation cascades,Regulates Actin and Cytoskeleton, Protein Expression Lung,Skin, Subcellular Localization endoplasmic reticulum,plasma membrane,integral component of plasma membrane,integral component of membrane,neuron projection, Protein Function function:This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation.,online information:Bradykinin receptor entry,similarity:Belongs to the G-protein coupled receptor 1 family., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | Bradykinin B1 R |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IF,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human BDKRB1. AA range:201-250 |
| Specificity | Bradykinin B1 R Polyclonal Antibody detects endogenous levels of Bradykinin B1 R protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | BDKRB1 |
| Accession No. | P46663 Q61125 |
| Alternate Names | BDKRB1; BRADYB1; B1 bradykinin receptor; B1R; BK-1 receptor |
| Description | bradykinin receptor B1(BDKRB1) Homo sapiens Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011], |
| Cell Pathway/ Category | Calcium,Neuroactive ligand-receptor interaction,Complement and coagulation cascades,Regulates Actin and Cytoskeleton, |
| Protein Expression | Lung,Skin, |
| Subcellular Localization | endoplasmic reticulum,plasma membrane,integral component of plasma membrane,integral component of membrane,neuron projection, |
| Protein Function | function:This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation.,online information:Bradykinin receptor entry,similarity:Belongs to the G-protein coupled receptor 1 family., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |