ITT1162
ITT1162
ITT1162
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Price in reward points: 424
- Catalog: ITT1162
- Gene/Protein: CXCR7
- Product Description: Immunotag™ CXCR-7 Polyclonal Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein CXCR-7 Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,IF,ELISA Recommended Dilution Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. Concentration 1 mg/ml Reactive Species Human,Mouse,Rat,Monkey Host Species Rabbit Immunogen Synthesized peptide derived from CXCR-7, at AA range: 290-370 Specificity CXCR-7 Polyclonal Antibody detects endogenous levels of CXCR-7 protein. Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Gene Name CXCR7 Accession No. P25106 P56485 O89039 Alternate Names CXCR7; CMKOR1; GPR159; RDC1; C-X-C chemokine receptor type 7; CXC-R7; CXCR-7; Chemokine orphan receptor 1; G-protein coupled receptor 159; G-protein coupled receptor RDC1 homolog; RDC-1 Description atypical chemokine receptor 3(ACKR3) Homo sapiens This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas. [provided by RefSeq, Jul 2008], Protein Expression Testis, Subcellular Localization endosome,early endosome,plasma membrane,clathrin-coated pit,cell surface,integral component of membrane,intracellular membrane-bounded organelle,perinuclear region of cytoplasm,recycling endosome, Protein Function caution:Was originally (PubMed:1675791) thought to be the receptor for VIP.,function:Receptor for CXCL12/SDF1. Acts as coreceptor with CXCR4 for a restricted number of HIV isolates.,online information:CXC chemokine receptors entry,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in monocytes, basophils, and B-cells. Lower expression in CD4+ T-lymphocytes and natural killer cells., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | CXCR-7 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IF,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat,Monkey |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from CXCR-7, at AA range: 290-370 |
| Specificity | CXCR-7 Polyclonal Antibody detects endogenous levels of CXCR-7 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | CXCR7 |
| Accession No. | P25106 P56485 O89039 |
| Alternate Names | CXCR7; CMKOR1; GPR159; RDC1; C-X-C chemokine receptor type 7; CXC-R7; CXCR-7; Chemokine orphan receptor 1; G-protein coupled receptor 159; G-protein coupled receptor RDC1 homolog; RDC-1 |
| Description | atypical chemokine receptor 3(ACKR3) Homo sapiens This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas. [provided by RefSeq, Jul 2008], |
| Protein Expression | Testis, |
| Subcellular Localization | endosome,early endosome,plasma membrane,clathrin-coated pit,cell surface,integral component of membrane,intracellular membrane-bounded organelle,perinuclear region of cytoplasm,recycling endosome, |
| Protein Function | caution:Was originally (PubMed:1675791) thought to be the receptor for VIP.,function:Receptor for CXCL12/SDF1. Acts as coreceptor with CXCR4 for a restricted number of HIV isolates.,online information:CXC chemokine receptors entry,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in monocytes, basophils, and B-cells. Lower expression in CD4+ T-lymphocytes and natural killer cells., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |