ITT1521
ITT1521
ITT1521
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Price in reward points: 424
- Catalog: ITT1521
- Gene/Protein: EIF5B
- Product Description: Immunotag™ eIF5B Polyclonal Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein EIF5B Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,IHC-p,ELISA Recommended Dilution Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. Concentration 1 mg/ml Reactive Species Human,Mouse,Rat Host Species Rabbit Immunogen Synthesized peptide derived from eIF5B, at AA range: 1020-1100 Specificity eIF5B Polyclonal Antibody detects endogenous levels of eIF5B protein. Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Gene Name EIF5B Accession No. O60841 Q05D44 B2GUV7 Alternate Names EIF5B; IF2; KIAA0741; Eukaryotic translation initiation factor 5B; eIF-5B; Translation initiation factor IF-2 Description eukaryotic translation initiation factor 5B(EIF5B) Homo sapiens Accurate initiation of translation in eukaryotes is complex and requires many factors, some of which are composed of multiple subunits. The process is simpler in prokaryotes which have only three initiation factors (IF1, IF2, IF3). Two of these factors are conserved in eukaryotes: the homolog of IF1 is eIF1A and the homolog of IF2 is eIF5B. This gene encodes eIF5B. Factors eIF1A and eIF5B interact on the ribosome along with other initiation factors and GTP to position the initiation methionine tRNA on the start codon of the mRNA so that translation initiates accurately. [provided by RefSeq, Jul 2008], Protein Expression Brain,Cervix carcinoma,Epithelium,Hepatocyte,Liver,Lymph,Pl Subcellular Localization nucleus,cytoplasm,cytosol, Protein Function function:Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.,similarity:Belongs to the IF-2 family.,subunit:Interacts with ANXA5 in a calcium and phospholipid-dependent manner., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | EIF5B |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from eIF5B, at AA range: 1020-1100 |
| Specificity | eIF5B Polyclonal Antibody detects endogenous levels of eIF5B protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | EIF5B |
| Accession No. | O60841 Q05D44 B2GUV7 |
| Alternate Names | EIF5B; IF2; KIAA0741; Eukaryotic translation initiation factor 5B; eIF-5B; Translation initiation factor IF-2 |
| Description | eukaryotic translation initiation factor 5B(EIF5B) Homo sapiens Accurate initiation of translation in eukaryotes is complex and requires many factors, some of which are composed of multiple subunits. The process is simpler in prokaryotes which have only three initiation factors (IF1, IF2, IF3). Two of these factors are conserved in eukaryotes: the homolog of IF1 is eIF1A and the homolog of IF2 is eIF5B. This gene encodes eIF5B. Factors eIF1A and eIF5B interact on the ribosome along with other initiation factors and GTP to position the initiation methionine tRNA on the start codon of the mRNA so that translation initiates accurately. [provided by RefSeq, Jul 2008], |
| Protein Expression | Brain,Cervix carcinoma,Epithelium,Hepatocyte,Liver,Lymph,Pl |
| Subcellular Localization | nucleus,cytoplasm,cytosol, |
| Protein Function | function:Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.,similarity:Belongs to the IF-2 family.,subunit:Interacts with ANXA5 in a calcium and phospholipid-dependent manner., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |