ITT1860
ITT1860
- Catalog: ITT1860
- Gene/Protein: GATA2/GATA3
- Product Description: Immunotag™ GATA-2/3 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | GATA-2/3 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,IF,ELISA |
Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human GATA3. AA range:274-323 |
Specificity | GATA-2/3 Polyclonal Antibody detects endogenous levels of GATA-2/3 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | GATA2/GATA3 |
Accession No. | P23771/P23769 |
Alternate Names | GATA3; Trans-acting T-cell-specific transcription factor GATA-3; GATA-binding factor 3; GATA2; Endothelial transcription factor GATA-2; GATA-binding protein 2 |
Description | GATA binding protein 3(GATA3) Homo sapiens This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia. [provided by RefSeq, Nov 2009], |
Protein Expression | Cervix,Placenta,T-cell, |
Subcellular Localization | nuclear chromatin,nucleus,nucleoplasm,transcription factor complex,nucleolus, |
Protein Function | disease:Defects in GATA3 are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia (HDR) [MIM:146255]; also known as Barakat syndrome.,function:Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'.,similarity:Contains 2 GATA-type zinc fingers.,tissue specificity:T-cells and endothelial cells., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |