ITT2752
ITT2752
ITT2752
from
$424.00
Price in reward points: 424
- Catalog: ITT2752
- Gene/Protein: MGST2
- Product Description: Immunotag™ MGST2 Polyclonal Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein MGST2 Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,ELISA Recommended Dilution Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. Concentration 1 mg/ml Reactive Species Human Host Species Rabbit Immunogen Synthesized peptide derived from MGST2 . at AA range: 370-450 Specificity MGST2 Polyclonal Antibody detects endogenous levels of MGST2 protein. Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Gene Name MGST2 Accession No. Q99735 Alternate Names MGST2; GST2; Microsomal glutathione S-transferase 2; Microsomal GST-2; Microsomal GST-II Description microsomal glutathione S-transferase 2(MGST2) Homo sapiens The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, several of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. This gene encodes a protein which catalyzes the conjugation of leukotriene A4 and reduced glutathione to produce leukotriene C4. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Feb 2011], Cell Pathway/ Category Glutathione metabolism,Metabolism of xenobiotics by cytochrome P450,Drug metabolism, Protein Expression Lung, Subcellular Localization nuclear envelope,endoplasmic reticulum,endoplasmic reticulum membrane,plasma membrane,integral component of membrane,organelle membrane,intracellular membrane-bounded organelle, Protein Function catalytic activity:RX + glutathione = HX + R-S-glutathione.,function:Can catalyze the production of LTC4 from LTA4 and reduced glutathione. Can catalyze the conjugation of 1-chloro-2,4-dinitrobenzene with reduced glutathione.,similarity:Belongs to the MAPEG family.,subunit:Homotrimer.,tissue specificity:Liver, spleen, skeletal muscle, heart, adrenals, pancreas, prostate, testis, fetal liver, and fetal spleen. Very low expression in lung, brain, placenta and bone marrow., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | MGST2 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from MGST2 . at AA range: 370-450 |
| Specificity | MGST2 Polyclonal Antibody detects endogenous levels of MGST2 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | MGST2 |
| Accession No. | Q99735 |
| Alternate Names | MGST2; GST2; Microsomal glutathione S-transferase 2; Microsomal GST-2; Microsomal GST-II |
| Description | microsomal glutathione S-transferase 2(MGST2) Homo sapiens The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, several of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. This gene encodes a protein which catalyzes the conjugation of leukotriene A4 and reduced glutathione to produce leukotriene C4. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Feb 2011], |
| Cell Pathway/ Category | Glutathione metabolism,Metabolism of xenobiotics by cytochrome P450,Drug metabolism, |
| Protein Expression | Lung, |
| Subcellular Localization | nuclear envelope,endoplasmic reticulum,endoplasmic reticulum membrane,plasma membrane,integral component of membrane,organelle membrane,intracellular membrane-bounded organelle, |
| Protein Function | catalytic activity:RX + glutathione = HX + R-S-glutathione.,function:Can catalyze the production of LTC4 from LTA4 and reduced glutathione. Can catalyze the conjugation of 1-chloro-2,4-dinitrobenzene with reduced glutathione.,similarity:Belongs to the MAPEG family.,subunit:Homotrimer.,tissue specificity:Liver, spleen, skeletal muscle, heart, adrenals, pancreas, prostate, testis, fetal liver, and fetal spleen. Very low expression in lung, brain, placenta and bone marrow., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |