ITT2753
ITT2753
ITT2753
from
$424.00
Price in reward points: 424
- Catalog: ITT2753
- Gene/Protein: MGST3
- Product Description: Immunotag™ MGST3 Polyclonal Antibody
-
Description
-
Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein MGST3 Clonality Polyclonal Storage/Stability -20°C/1 year Application IHC-p,ELISA Recommended Dilution Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. Concentration 1 mg/ml Reactive Species Human,Mouse Host Species Rabbit Immunogen The antiserum was produced against synthesized peptide derived from human MGST3. AA range:8-57 Specificity MGST3 Polyclonal Antibody detects endogenous levels of MGST3 protein. Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Gene Name MGST3 Accession No. O14880 Q9CPU4 Alternate Names MGST3; Microsomal glutathione S-transferase 3; Microsomal GST-3; Microsomal GST-III Description microsomal glutathione S-transferase 3(MGST3) Homo sapiens This gene encodes a member of the MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) protein family. Members of this family are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. This gene encodes an enzyme which catalyzes the conjugation of leukotriene A4 and reduced glutathione to produce leukotriene C4. This enzyme also demonstrates glutathione-dependent peroxidase activity towards lipid hydroperoxides.[provided by RefSeq, May 2011], Cell Pathway/ Category Glutathione metabolism,Metabolism of xenobiotics by cytochrome P450,Drug metabolism, Protein Expression Human small intestine,Kidney,Lung, Subcellular Localization nuclear envelope,endoplasmic reticulum,endoplasmic reticulum membrane,membrane,integral component of membrane,organelle membrane,intracellular membrane-bounded organelle,extracellular exosome, Protein Function catalytic activity:RX + glutathione = HX + R-S-glutathione.,function:Also functions as a glutathione peroxidase.,similarity:Belongs to the MAPEG family.,tissue specificity:Predominantly expressed in heart, skeletal muscle, and adrenal cortex. Also found in brain, placenta, liver, kidney, pancreas, thyroid, testis and ovary. Almost absent in lung, thymus and peripheral blood leukocytes., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | MGST3 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p,ELISA |
| Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MGST3. AA range:8-57 |
| Specificity | MGST3 Polyclonal Antibody detects endogenous levels of MGST3 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | MGST3 |
| Accession No. | O14880 Q9CPU4 |
| Alternate Names | MGST3; Microsomal glutathione S-transferase 3; Microsomal GST-3; Microsomal GST-III |
| Description | microsomal glutathione S-transferase 3(MGST3) Homo sapiens This gene encodes a member of the MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) protein family. Members of this family are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. This gene encodes an enzyme which catalyzes the conjugation of leukotriene A4 and reduced glutathione to produce leukotriene C4. This enzyme also demonstrates glutathione-dependent peroxidase activity towards lipid hydroperoxides.[provided by RefSeq, May 2011], |
| Cell Pathway/ Category | Glutathione metabolism,Metabolism of xenobiotics by cytochrome P450,Drug metabolism, |
| Protein Expression | Human small intestine,Kidney,Lung, |
| Subcellular Localization | nuclear envelope,endoplasmic reticulum,endoplasmic reticulum membrane,membrane,integral component of membrane,organelle membrane,intracellular membrane-bounded organelle,extracellular exosome, |
| Protein Function | catalytic activity:RX + glutathione = HX + R-S-glutathione.,function:Also functions as a glutathione peroxidase.,similarity:Belongs to the MAPEG family.,tissue specificity:Predominantly expressed in heart, skeletal muscle, and adrenal cortex. Also found in brain, placenta, liver, kidney, pancreas, thyroid, testis and ovary. Almost absent in lung, thymus and peripheral blood leukocytes., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |