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ITT3132

ITT3132
ITT3132
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$424.00
Price in reward points: 424
  • Catalog: ITT3132
  • Gene/Protein: TACR2
  • Product Description: Immunotag™ NK-2R Polyclonal Antibody

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Immunotag™ NK-2R Polyclonal Antibody
Antibody Specification
Datasheet
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return.
Target Protein NK-2R
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IF,ELISA
Recommended Dilution Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human
Host Species Rabbit
Immunogen The antiserum was produced against synthesized peptide derived from human NK2R. AA range:301-350
Specificity NK-2R Polyclonal Antibody detects endogenous levels of NK-2R protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name TACR2
Accession No. P21452 P30549
Alternate Names TACR2; NK2R; NKNAR; TAC2R; Substance-K receptor; SKR; NK-2 receptor; NK-2R; Neurokinin A receptor; Tachykinin receptor 2
Description tachykinin receptor 2(TACR2) Homo sapiens This gene belongs to a family of genes that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5'-end of the sequence. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin neuropeptide substance K, also referred to as neurokinin A. [provided by RefSeq, Jul 2008],
Cell Pathway/ Category Calcium,Neuroactive ligand-receptor interaction,
Protein Expression Bone marrow,Lung,Stomach,Trachea,
Subcellular Localization plasma membrane,integral component of plasma membrane,integral component of membrane,
Protein Function function:This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.,miscellaneous:The rank order of affinity of this receptor to tachykinins is: substance K > neuromedin-K > substance P.,similarity:Belongs to the G-protein coupled receptor 1 family.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.

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