ITT3179
ITT3179
- Catalog: ITT3179
- Gene/Protein: NPAS4
- Product Description: Immunotag™ NPAS4 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | NPAS4 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | IHC-p,ELISA |
Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from NPAS4, at AA range: 580-660 |
Specificity | NPAS4 Polyclonal Antibody detects endogenous levels of NPAS4 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | NPAS4 |
Accession No. | Q8IUM7 Q8BGD7 Q8CJH6 |
Alternate Names | NPAS4; BHLHE79; NXF; PASD10; Neuronal PAS domain-containing protein 4; Neuronal PAS4; Class E basic helix-loop-helix protein 79; bHLHe79; HLH-PAS transcription factor NXF; PAS domain-containing protein 10 |
Description | neuronal PAS domain protein 4(NPAS4) Homo sapiens NXF is a member of the basic helix-loop-helix-PER (MIM 602260)-ARNT (MIM 126110)-SIM (see SIM2; MIM 600892) (bHLH-PAS) class of transcriptional regulators, which are involved in a wide range of physiologic and developmental events (Ooe et al., 2004 [PubMed 14701734]).[supplied by OMIM, Mar 2008], |
Protein Expression | Brain,Fetal brain,Uterus, |
Subcellular Localization | nucleus,transcription factor complex,postsynapse, |
Protein Function | function:Acts as a transcriptional activator in the presence of ARNT. Can activate the CME (CNS midline enhancer) element and the expression of the drebrin gene.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,similarity:Contains 1 PAC (PAS-associated C-terminal) domain.,similarity:Contains 2 PAS (PER-ARNT-SIM) domains.,subunit:Efficient DNA binding requires dimerization with another bHLH protein. Forms a heterodimer with ARNT.,tissue specificity:Brain., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |