ITT3651
ITT3651
ITT3651
from
$424.00
Price in reward points: 424
- Catalog: ITT3651
- Gene/Protein: PDZD2
- Product Description: Immunotag™ PDZK3 Polyclonal Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein PDZK3 Clonality Polyclonal Storage/Stability -20°C/1 year Application IHC-p,IF,ELISA Recommended Dilution Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. Concentration 1 mg/ml Reactive Species Human,Mouse,Rat Host Species Rabbit Immunogen Synthesized peptide derived from PDZK3, at AA range: 30-110 Specificity PDZK3 Polyclonal Antibody detects endogenous levels of PDZK3 protein. Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Gene Name PDZD2 Accession No. O15018 Q9QZR8 Alternate Names PDZD2; AIPC; KIAA0300; PDZK3; PDZ domain-containing protein 2; Activated in prostate cancer protein; PDZ domain-containing protein 3 Description PDZ domain containing 2(PDZD2) Homo sapiens The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis. [provided by RefSeq, Dec 2015], Protein Expression Brain,Uterus, Subcellular Localization extracellular region,nucleus,cytoplasm,endoplasmic reticulum,cell-cell junction, Protein Function disease:May be associated with the early promotion of prostate tumoregenesis.,PTM:A secreted form is produced by caspase-mediated proteolytic cleavage.,similarity:Contains 1 PDZ (DHR) domain.,similarity:Contains 6 PDZ (DHR) domains.,subcellular location:At cell-cell contacts in lung epithelial cells.,subunit:Interacts with SCN10A, CTNND2 and PKP4.,tissue specificity:Expressed (at protein level) in prostate and many prostate tumors., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | PDZK3 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p,IF,ELISA |
| Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from PDZK3, at AA range: 30-110 |
| Specificity | PDZK3 Polyclonal Antibody detects endogenous levels of PDZK3 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | PDZD2 |
| Accession No. | O15018 Q9QZR8 |
| Alternate Names | PDZD2; AIPC; KIAA0300; PDZK3; PDZ domain-containing protein 2; Activated in prostate cancer protein; PDZ domain-containing protein 3 |
| Description | PDZ domain containing 2(PDZD2) Homo sapiens The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis. [provided by RefSeq, Dec 2015], |
| Protein Expression | Brain,Uterus, |
| Subcellular Localization | extracellular region,nucleus,cytoplasm,endoplasmic reticulum,cell-cell junction, |
| Protein Function | disease:May be associated with the early promotion of prostate tumoregenesis.,PTM:A secreted form is produced by caspase-mediated proteolytic cleavage.,similarity:Contains 1 PDZ (DHR) domain.,similarity:Contains 6 PDZ (DHR) domains.,subcellular location:At cell-cell contacts in lung epithelial cells.,subunit:Interacts with SCN10A, CTNND2 and PKP4.,tissue specificity:Expressed (at protein level) in prostate and many prostate tumors., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |