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ITT3651

ITT3651
  • Catalog: ITT3651
  • Gene/Protein: PDZD2
  • Product Description: Immunotag™ PDZK3 Polyclonal Antibody
385.0000
Price in reward points: 385

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Immunotag™ PDZK3 Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein PDZK3
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application IHC-p,IF,ELISA
Recommended Dilution Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human,Mouse,Rat
Host Species Rabbit
Immunogen Synthesized peptide derived from PDZK3, at AA range: 30-110
Specificity PDZK3 Polyclonal Antibody detects endogenous levels of PDZK3 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name PDZD2
Accession No. O15018 Q9QZR8
Alternate Names PDZD2; AIPC; KIAA0300; PDZK3; PDZ domain-containing protein 2; Activated in prostate cancer protein; PDZ domain-containing protein 3
Description PDZ domain containing 2(PDZD2) Homo sapiens The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis. [provided by RefSeq, Dec 2015],
Protein Expression Brain,Uterus,
Subcellular Localization extracellular region,nucleus,cytoplasm,endoplasmic reticulum,cell-cell junction,
Protein Function disease:May be associated with the early promotion of prostate tumoregenesis.,PTM:A secreted form is produced by caspase-mediated proteolytic cleavage.,similarity:Contains 1 PDZ (DHR) domain.,similarity:Contains 6 PDZ (DHR) domains.,subcellular location:At cell-cell contacts in lung epithelial cells.,subunit:Interacts with SCN10A, CTNND2 and PKP4.,tissue specificity:Expressed (at protein level) in prostate and many prostate tumors.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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