ITT3688
ITT3688
- Catalog: ITT3688
- Gene/Protein: PGD
- Product Description: Immunotag™ PGD Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | PGD |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,ELISA |
Recommended Dilution | IHC-p: 100-300.Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from PGD, at AA range: 40-120 |
Specificity | PGD Polyclonal Antibody detects endogenous levels of PGD protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | PGD |
Accession No. | P52209 Q9DCD0 P85968 |
Alternate Names | PGD; PGDH; 6-phosphogluconate dehydrogenase; decarboxylating |
Description | phosphogluconate dehydrogenase(PGD) Homo sapiens 6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015], |
Cell Pathway/ Category | Pentose phosphate pathway,Glutathione metabolism, |
Protein Expression | Heart,Lung, |
Subcellular Localization | nucleus,cytosol,extracellular exosome, |
Protein Function | catalytic activity:6-phospho-D-gluconate + NADP(+) = D-ribulose 5-phosphate + CO(2) + NADPH.,pathway:Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 3/3.,similarity:Belongs to the 6-phosphogluconate dehydrogenase family.,subunit:Homodimer., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |