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ITT3800

ITT3800
ITT3800-2
ITT3800
ITT3800-2
ITT3800
  • Gene/Protein: PMEPA1
  • Product Description: Immunotag™ PMEPA1 Polyclonal Antibody
280.0000
Price in reward points: 294

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Immunotag™ PMEPA1 Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein PMEPA1
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IHC-p,IF,ELISA
Recommended Dilution Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human
Host Species Rabbit
Immunogen The antiserum was produced against synthesized peptide derived from human TMEPA. AA range:101-150
Specificity PMEPA1 Polyclonal Antibody detects endogenous levels of PMEPA1 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name PMEPA1
Accession No. Q969W9 Q9D7R2
Alternate Names PMEPA1; STAG1; TMEPAI; Transmembrane prostate androgen-induced protein; Solid tumor-associated 1 protein
Description prostate transmembrane protein, androgen induced 1(PMEPA1) Homo sapiens This gene encodes a transmembrane protein that contains a Smad interacting motif (SIM). Expression of this gene is induced by androgens and transforming growth factor beta, and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins. Overexpression of this gene may play a role in multiple types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011],
Protein Expression Breast,Kidney,Thalamus,
Subcellular Localization Golgi membrane,nucleoplasm,plasma membrane,endosome membrane,integral component of membrane,early endosome membrane,intracellular membrane-bounded organelle,
Protein Function domain:The WW-binding motifs mediate interaction with NEDD4.,induction:By androgen.,similarity:Belongs to the PMEPA1 family.,subunit:Interacts with the WW domains of NEDD4.,tissue specificity:Highest expression in prostate. Also expressed in ovary.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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