ITT3800
ITT3800
ITT3800
from
$424.00
Price in reward points: 424
- Catalog: ITT3800
- Gene/Protein: PMEPA1
- Product Description: Immunotag™ PMEPA1 Polyclonal Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein PMEPA1 Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,IHC-p,IF,ELISA Recommended Dilution Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. Concentration 1 mg/ml Reactive Species Human Host Species Rabbit Immunogen The antiserum was produced against synthesized peptide derived from human TMEPA. AA range:101-150 Specificity PMEPA1 Polyclonal Antibody detects endogenous levels of PMEPA1 protein. Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Gene Name PMEPA1 Accession No. Q969W9 Q9D7R2 Alternate Names PMEPA1; STAG1; TMEPAI; Transmembrane prostate androgen-induced protein; Solid tumor-associated 1 protein Description prostate transmembrane protein, androgen induced 1(PMEPA1) Homo sapiens This gene encodes a transmembrane protein that contains a Smad interacting motif (SIM). Expression of this gene is induced by androgens and transforming growth factor beta, and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins. Overexpression of this gene may play a role in multiple types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011], Protein Expression Breast,Kidney,Thalamus, Subcellular Localization Golgi membrane,nucleoplasm,plasma membrane,endosome membrane,integral component of membrane,early endosome membrane,intracellular membrane-bounded organelle, Protein Function domain:The WW-binding motifs mediate interaction with NEDD4.,induction:By androgen.,similarity:Belongs to the PMEPA1 family.,subunit:Interacts with the WW domains of NEDD4.,tissue specificity:Highest expression in prostate. Also expressed in ovary., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | PMEPA1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,IF,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human TMEPA. AA range:101-150 |
| Specificity | PMEPA1 Polyclonal Antibody detects endogenous levels of PMEPA1 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | PMEPA1 |
| Accession No. | Q969W9 Q9D7R2 |
| Alternate Names | PMEPA1; STAG1; TMEPAI; Transmembrane prostate androgen-induced protein; Solid tumor-associated 1 protein |
| Description | prostate transmembrane protein, androgen induced 1(PMEPA1) Homo sapiens This gene encodes a transmembrane protein that contains a Smad interacting motif (SIM). Expression of this gene is induced by androgens and transforming growth factor beta, and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins. Overexpression of this gene may play a role in multiple types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011], |
| Protein Expression | Breast,Kidney,Thalamus, |
| Subcellular Localization | Golgi membrane,nucleoplasm,plasma membrane,endosome membrane,integral component of membrane,early endosome membrane,intracellular membrane-bounded organelle, |
| Protein Function | domain:The WW-binding motifs mediate interaction with NEDD4.,induction:By androgen.,similarity:Belongs to the PMEPA1 family.,subunit:Interacts with the WW domains of NEDD4.,tissue specificity:Highest expression in prostate. Also expressed in ovary., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |