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ITT3805

ITT3805
  • Catalog: ITT3805
  • Gene/Protein: PMS2/PMS2CL
  • Product Description: Immunotag™ PMS2/PMS2CL Polyclonal Antibody
385.0000
Price in reward points: 385

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Immunotag™ PMS2/PMS2CL Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein PMS2/PMS2CL
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application IHC-p,ELISA
Recommended Dilution Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human
Host Species Rabbit
Immunogen The antiserum was produced against synthesized peptide derived from human PMS2CL. AA range:125-174
Specificity PMS2/PMS2CL Polyclonal Antibody detects endogenous levels of PMS2/PMS2CL protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name PMS2/PMS2CL
Accession No. Q68D20/P54278
Alternate Names PMS2CL; Protein PMS2CL; PMS2-C terminal-like protein; PMS2; PMSL2; Mismatch repair endonuclease PMS2; DNA mismatch repair protein PMS2; PMS1 protein homolog 2
Description caution:According to PubMed:15077197, it is a pseudogene. However, a peptide specific to this protein was identified by mass spectrometry (PubMed:17525332). Given that the product described by PubMed:15077197 is located downstream and on another frame of the transcript, it may explain why PubMed:15256438 could not detect this protein on a Western blot.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Wrong choice of transcript.,similarity:Belongs to the DNA mismatch repair mutL/hexB family.,
Protein Expression Fetal brain,Testis,
Subcellular Localization mismatch repair complex,
Protein Function caution:According to PubMed:15077197, it is a pseudogene. However, a peptide specific to this protein was identified by mass spectrometry (PubMed:17525332). Given that the product described by PubMed:15077197 is located downstream and on another frame of the transcript, it may explain why PubMed:15256438 could not detect this protein on a Western blot.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Wrong choice of transcript.,similarity:Belongs to the DNA mismatch repair mutL/hexB family.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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