ITT3955
ITT3955
ITT3955
from
$424.00
Price in reward points: 424
- Catalog: ITT3955
- Gene/Protein: ZMYND8
- Product Description: Immunotag™ RACK7 Polyclonal Antibody
-
Description
-
Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein RACK7 Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,IF,ELISA Recommended Dilution Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. Concentration 1 mg/ml Reactive Species Human Host Species Rabbit Immunogen The antiserum was produced against synthesized peptide derived from human PKCB1. AA range:581-630 Specificity RACK7 Polyclonal Antibody detects endogenous levels of RACK7 protein. Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Gene Name ZMYND8 Accession No. Q9ULU4 Alternate Names ZMYND8; KIAA1125; PRKCBP1; RACK7; Protein kinase C-binding protein 1; Cutaneous T-cell lymphoma-associated antigen se14-3; CTCL-associated antigen se14-3; Rack7; Zinc finger MYND domain-containing protein 8 Description zinc finger MYND-type containing 8(ZMYND8) Homo sapiens The protein encoded by this gene is a receptor for activated C-kinase (RACK) protein. The encoded protein has been shown to bind in vitro to activated protein kinase C beta I. In addition, this protein is a cutaneous T-cell lymphoma-associated antigen. Finally, the protein contains a bromodomain and two zinc fingers, and is thought to be a transcriptional regulator. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], Protein Expression Brain,Epithelium,Eye,Hippocampus,Liver,Mammary tumor,Salivary gland Subcellular Localization nucleus,cytoplasm,dendritic spine,dendritic shaft, Protein Function PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 bromo domain.,similarity:Contains 1 MYND-type zinc finger.,similarity:Contains 1 PHD-type zinc finger.,similarity:Contains 1 PWWP domain.,subunit:Interacts in vitro with PRKCB1.,tissue specificity:Expressed in all tissues examined with highest expression in brain, lung, pancreas, and placenta. Expressed in cutaneous T-cell lymphomas (CTCL)., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | RACK7 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IF,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human PKCB1. AA range:581-630 |
| Specificity | RACK7 Polyclonal Antibody detects endogenous levels of RACK7 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | ZMYND8 |
| Accession No. | Q9ULU4 |
| Alternate Names | ZMYND8; KIAA1125; PRKCBP1; RACK7; Protein kinase C-binding protein 1; Cutaneous T-cell lymphoma-associated antigen se14-3; CTCL-associated antigen se14-3; Rack7; Zinc finger MYND domain-containing protein 8 |
| Description | zinc finger MYND-type containing 8(ZMYND8) Homo sapiens The protein encoded by this gene is a receptor for activated C-kinase (RACK) protein. The encoded protein has been shown to bind in vitro to activated protein kinase C beta I. In addition, this protein is a cutaneous T-cell lymphoma-associated antigen. Finally, the protein contains a bromodomain and two zinc fingers, and is thought to be a transcriptional regulator. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], |
| Protein Expression | Brain,Epithelium,Eye,Hippocampus,Liver,Mammary tumor,Salivary gland |
| Subcellular Localization | nucleus,cytoplasm,dendritic spine,dendritic shaft, |
| Protein Function | PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 bromo domain.,similarity:Contains 1 MYND-type zinc finger.,similarity:Contains 1 PHD-type zinc finger.,similarity:Contains 1 PWWP domain.,subunit:Interacts in vitro with PRKCB1.,tissue specificity:Expressed in all tissues examined with highest expression in brain, lung, pancreas, and placenta. Expressed in cutaneous T-cell lymphomas (CTCL)., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |