ITT3999
ITT3999
- Catalog: ITT3999
- Gene/Protein: RANBP17
- Product Description: Immunotag™ Ran BP-17 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | Ran BP-17 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human RANBP17. AA range:145-194 |
Specificity | Ran BP-17 Polyclonal Antibody detects endogenous levels of Ran BP-17 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | RANBP17 |
Accession No. | Q9H2T7 Q99NF8 |
Alternate Names | RANBP17; Ran-binding protein 17 |
Description | RAN binding protein 17(RANBP17) Homo sapiens The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-17 is a member of the importin-beta superfamily of nuclear transport receptors.[supplied by OMIM, Jul 2002], |
Protein Expression | Cervix carcinoma,Stomach,Testis,Thyroid, |
Subcellular Localization | intracellular,nuclear pore,cytoplasm, |
Protein Function | function:May function as a nuclear transport receptor.,similarity:Belongs to the exportin family.,subunit:Binds to nucleoporins and the GTP-bound form of Ran.,tissue specificity:Highly expressed in testis, moderately in pancreas and weakly in other tissues studied., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |