ITT4158
ITT4158
ITT4158
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$424.00
Price in reward points: 424
- Catalog: ITT4158
- Gene/Protein: USP6NL
- Product Description: Immunotag™ RN-tre Polyclonal Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein RN-tre Clonality Polyclonal Storage/Stability -20°C/1 year Application IHC-p,ELISA Recommended Dilution Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. Concentration 1 mg/ml Reactive Species Human Host Species Rabbit Immunogen The antiserum was produced against synthesized peptide derived from human USP6NL. AA range:451-500 Specificity RN-tre Polyclonal Antibody detects endogenous levels of RN-tre protein. Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Gene Name USP6NL Accession No. Q92738 Q80XC3 Alternate Names USP6NL; KIAA0019; USP6 N-terminal-like protein; Related to the N-terminus of tre; RN-tre Description function:Acts as a GTPase-activating protein for RAB5A. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 Rab-GAP TBC domain.,subunit:Interacts with EPS8.,tissue specificity:Widely expressed., Protein Expression Bone marrow,Brain,Epithelium,T-cell,Testis, Subcellular Localization cytosol,plasma membrane,endomembrane system,cytoplasmic, membrane-bounded vesicle,cytoplasmic vesicle,trans-Golgi network membrane, Protein Function function:Acts as a GTPase-activating protein for RAB5A. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 Rab-GAP TBC domain.,subunit:Interacts with EPS8.,tissue specificity:Widely expressed., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | RN-tre |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p,ELISA |
| Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human USP6NL. AA range:451-500 |
| Specificity | RN-tre Polyclonal Antibody detects endogenous levels of RN-tre protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | USP6NL |
| Accession No. | Q92738 Q80XC3 |
| Alternate Names | USP6NL; KIAA0019; USP6 N-terminal-like protein; Related to the N-terminus of tre; RN-tre |
| Description | function:Acts as a GTPase-activating protein for RAB5A. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 Rab-GAP TBC domain.,subunit:Interacts with EPS8.,tissue specificity:Widely expressed., |
| Protein Expression | Bone marrow,Brain,Epithelium,T-cell,Testis, |
| Subcellular Localization | cytosol,plasma membrane,endomembrane system,cytoplasmic, membrane-bounded vesicle,cytoplasmic vesicle,trans-Golgi network membrane, |
| Protein Function | function:Acts as a GTPase-activating protein for RAB5A. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 Rab-GAP TBC domain.,subunit:Interacts with EPS8.,tissue specificity:Widely expressed., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |